Cargando…
Drug Repurposing Approaches towards Defeating Multidrug-Resistant Gram-Negative Pathogens: Novel Polymyxin/Non-Antibiotic Combinations
Multidrug-resistant (MDR) Gram-negative pathogens remain an unmet public health threat. In recent times, increased rates of resistance have been reported not only to commonly used antibiotics, but also to the last-resort antibiotics, such as polymyxins. More worryingly, despite the current trends in...
Autores principales: | Koh Jing Jie, Augustine, Hussein, Maytham, Rao, Gauri G., Li, Jian, Velkov, Tony |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781023/ https://www.ncbi.nlm.nih.gov/pubmed/36558754 http://dx.doi.org/10.3390/pathogens11121420 |
Ejemplares similares
-
Polymyxin B combinations with FDA-approved non-antibiotic phenothiazine drugs targeting multi-drug resistance of Gram-negative pathogens
por: Hussein, Maytham, et al.
Publicado: (2020) -
Novel Polymyxin Combination With Antineoplastic Mitotane Improved the Bacterial Killing Against Polymyxin-Resistant Multidrug-Resistant Gram-Negative Pathogens
por: Tran, Thien B., et al.
Publicado: (2018) -
Bifunctional antibiotic hybrids: A review of clinical candidates
por: Koh, Augustine Jing Jie, et al.
Publicado: (2023) -
Unique mechanistic insights into pathways associated with the synergistic activity of polymyxin B and caspofungin against multidrug-resistant Klebsiella pneumoniae
por: Hussein, Maytham, et al.
Publicado: (2022) -
Mechanisms Underlying Synergistic Killing of Polymyxin B in Combination with Cannabidiol against Acinetobacter baumannii: A Metabolomic Study
por: Hussein, Maytham, et al.
Publicado: (2022)