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Alternative Excipients for Protein Stabilization in Protein Therapeutics: Overcoming the Limitations of Polysorbates

Given their safety and efficiency in protecting protein integrity, polysorbates (PSs) have been the most widely used excipients for the stabilization of protein therapeutics for years. In recent decades, however, there have been numerous reports about visible or sub-visible particles in PS-containin...

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Detalles Bibliográficos
Autores principales: Castañeda Ruiz, Angel J., Shetab Boushehri, Maryam A., Phan, Tamara, Carle, Stefan, Garidel, Patrick, Buske, Julia, Lamprecht, Alf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781097/
https://www.ncbi.nlm.nih.gov/pubmed/36559072
http://dx.doi.org/10.3390/pharmaceutics14122575