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Artificial Base-Directed In Vivo Formulation of Aptamer–Drug Conjugates with Albumin for Long Circulation and Targeted Delivery

Aptamer–drug conjugates (ApDCs) are potential targeted pharmaceutics, but their clinical applications are hampered by fast clearance in blood. Herein we report the construction of ApDCs modified with artificial base F and the study of biological activities. Two types of F-base-modified ApDCs were pr...

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Detalles Bibliográficos
Autores principales:	Sun, Yang, Geng, Xinyao, Ma, Yue, Qin, Yu, Hu, Shangjiu, Xie, Yuquan, Wang, Ruowen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781099/ https://www.ncbi.nlm.nih.gov/pubmed/36559275 http://dx.doi.org/10.3390/pharmaceutics14122781

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