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A High-Throughput Fluorescence Polarization-Based Assay for the SH2 Domain of STAT4

The signal transducer and activation of transcription (STAT) proteins are a family of Src homology 2 (SH2) domain-containing transcription factors. The family member STAT4 is a mediator of IL-12 signalling and has been implicated in the pathogenesis of multiple autoimmune diseases. The activity of S...

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Detalles Bibliográficos
Autores principales: Berg, Angela, Gräber, Martin, Schmutzler, Sebastian, Hoffmann, Ralf, Berg, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781101/
https://www.ncbi.nlm.nih.gov/pubmed/36548135
http://dx.doi.org/10.3390/mps5060093