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Pharmacokinetic Study and Metabolite Identification of 1-(3′-bromophenyl)-heliamine in Rats
Tetrahydroisoquinolines have been widely investigated for the treatment of arrhythmias. 1−(3′−bromophenyl)−heliamine (BH), an anti−arrhythmias agent, is a synthetic tetrahydroisoquinoline. This study focuses on the pharmacokinetic characterization of BH, as well as the identification of its metaboli...
Autores principales: | Xi, Ruqi, Abdulla, Rahima, Zhang, Miaomiao, Sherzod, Zhurakulov, Ivanovna, Vinogradova Valentina, Habasi, Maidina, Liu, Yongqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781129/ https://www.ncbi.nlm.nih.gov/pubmed/36558934 http://dx.doi.org/10.3390/ph15121483 |
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