Validation of a Dendritic Cell and CD4+ T Cell Restimulation Assay Contributing to the Immunogenicity Risk Evaluation of Biotherapeutics

Immunogenicity, defined as the ability to provoke an immune response, can be either wanted (i.e., vaccines) or unwanted. The latter refers to an immune response to protein or peptide therapeutics, characterized by the production of anti-drug antibodies, which may affect the efficacy and/or the safet...

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Detalles Bibliográficos
Autores principales: Siegel, Michel, Steiner, Guido, Franssen, Linnea C., Carratu, Francesca, Herron, James, Hartman, Katharina, Looney, Cary M., Ducret, Axel, Bray-French, Katharine, Rohr, Olivier, Hickling, Timothy P., Smith, Noel, Marban-Doran, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781343/
https://www.ncbi.nlm.nih.gov/pubmed/36559166
http://dx.doi.org/10.3390/pharmaceutics14122672

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