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The Modular Architecture of Metallothioneins Facilitates Domain Rearrangements and Contributes to Their Evolvability in Metal-Accumulating Mollusks
Protein domains are independent structural and functional modules that can rearrange to create new proteins. While the evolution of multidomain proteins through the shuffling of different preexisting domains has been well documented, the evolution of domain repeat proteins and the origin of new doma...
Autores principales: | Calatayud, Sara, Garcia-Risco, Mario, Pedrini-Martha, Veronika, Niederwanger, Michael, Dallinger, Reinhard, Palacios, Òscar, Capdevila, Mercè, Albalat, Ricard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781358/ https://www.ncbi.nlm.nih.gov/pubmed/36555472 http://dx.doi.org/10.3390/ijms232415824 |
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