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Rare Amyloid Precursor Protein Point Mutations Recapitulate Worldwide Migration and Admixture in Healthy Individuals: Implications for the Study of Neurodegeneration

Genetic discoveries related to Alzheimer’s disease and other dementias have been performed using either large cohorts of affected subjects or multiple individuals from the same pedigree, therefore disregarding mutations in the context of healthy groups. Moreover, a large portion of studies so far ha...

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Detalles Bibliográficos
Autores principales: Abondio, Paolo, Bruno, Francesco, Bruni, Amalia Cecilia, Luiselli, Donata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781461/
https://www.ncbi.nlm.nih.gov/pubmed/36555510
http://dx.doi.org/10.3390/ijms232415871