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IL-10-Secreting CD8(+) T Cells Specific for Human Cytomegalovirus (HCMV): Generation, Maintenance and Phenotype

HCMV-specific CD8(+) T-cells are potent anti-viral effector cells in HCMV infected individuals, but evidence from other viral infections suggests that CD8(+) T-cells can also produce the immunomodulatory cytokine IL-10. In this work we show that there are HCMV-specific IL-10 CD8(+) T-cell responses...

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Detalles Bibliográficos
Autores principales: Jackson, Sarah E., Sedikides, George X., Romashova, Veronika, Okecha, Georgina, Remmerswaal, Ester B. M., Bemelman, Frederike J., Sinclair, John H., Wills, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781655/
https://www.ncbi.nlm.nih.gov/pubmed/36558866
http://dx.doi.org/10.3390/pathogens11121530