Cargando…

Integrated Analysis Revealed an Inflammatory Cancer-Associated Fibroblast-Based Subtypes with Promising Implications in Predicting the Prognosis and Immunotherapeutic Response of Bladder Cancer Patients

Inflammatory cancer-associated fibroblasts (iCAFs) are closely related to progression, anticancer therapeutic resistance, and poor prognosis of bladder cancer (BCa). However, the functional role of iCAFs in BCa has been poorly studied. In our study, two BCa scRNA-seq datasets (GSE130001 and GSE14613...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Hualin, Yang, Wenjie, Xue, Xiaoqiang, Li, Yingjie, Jin, Zhaoheng, Ji, Zhigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781727/ https://www.ncbi.nlm.nih.gov/pubmed/36555612 http://dx.doi.org/10.3390/ijms232415970

Ejemplares similares

Neoadjuvant immunotherapy and chemoimmunotherapy for stage II-III muscle invasive bladder cancer
por: Chen, Hualin, et al.
Publicado: (2022)

A comprehensive analysis of the FOX family for predicting kidney renal clear cell carcinoma prognosis and the oncogenic role of FOXG1
por: Yang, Wenjie, et al.
Publicado: (2022)

SHOX2 promotes prostate cancer proliferation and metastasis through disruption of the Hippo-YAP pathway
por: Yang, Wenjie, et al.
Publicado: (2023)

Machine learning to improve prognosis prediction of metastatic clear-cell renal cell carcinoma treated with cytoreductive nephrectomy and systemic therapy
por: Yang, Wenjie, et al.
Publicado: (2023)

Identification of an IRGP Signature to Predict Prognosis and Immunotherapeutic Efficiency in Bladder Cancer
por: Zhang, Liang-Hao, et al.
Publicado: (2021)

Machine learning-based identification of tumor-infiltrating immune cell-associated model with appealing implications in improving prognosis and immunotherapy response in bladder cancer patients
por: Chen, Hualin, et al.
Publicado: (2023)

Immunotherapeutic strategies for bladder cancer
por: Chevalier, Mathieu F, et al.
Publicado: (2014)

PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling
por: Chen, Hualin, et al.
Publicado: (2023)

Leveraging a disulfidptosis-based signature to improve the survival and drug sensitivity of bladder cancer patients
por: Chen, Hualin, et al.
Publicado: (2023)

DNA methylation-based lung adenocarcinoma subtypes can predict prognosis, recurrence, and immunotherapeutic implications
por: Xu, Feng, et al.
Publicado: (2020)

Crosstalk between Mesenchymal Stem Cells and Cancer Stem Cells Reveals a Novel Stemness-Related Signature to Predict Prognosis and Immunotherapy Responses for Bladder Cancer Patients
por: Ma, Lin, et al.
Publicado: (2023)

Identification of immune-related LncRNA for predicting prognosis and immunotherapeutic response in bladder cancer
por: Wu, Yucai, et al.
Publicado: (2020)

The Ferroptosis Molecular Subtype Reveals Characteristics of the Tumor Microenvironment, Immunotherapeutic Response, and Prognosis in Gastric Cancer
por: Xu, Xiao, et al.
Publicado: (2022)

A cancer-associated fibroblast subtypes-based signature enables the evaluation of immunotherapy response and prognosis in bladder cancer
por: Qin, Yiming, et al.
Publicado: (2023)

MEK is a promising target in the basal subtype of bladder cancer
por: Merrill, Nathan M., et al.
Publicado: (2020)

Identification and validation of tumor-infiltrating lymphocyte-related prognosis signature for predicting prognosis and immunotherapeutic response in bladder cancer
por: Li, Canxuan, et al.
Publicado: (2023)

Identification of Immune-Related lncRNA Signature to Predict Prognosis and Immunotherapeutic Efficiency in Bladder Cancer
por: Zhang, Lianghao, et al.
Publicado: (2021)

An Immunosenescence-Related Gene Signature to Evaluate the Prognosis, Immunotherapeutic Response, and Cisplatin Sensitivity of Bladder Cancer
por: Zhou, Ranran, et al.
Publicado: (2022)

T Lymphocytes: A Promising Immunotherapeutic Target for Pancreatitis and Pancreatic Cancer?
por: Zhou, Qi, et al.
Publicado: (2020)

Promising immunotherapeutic targets in lung cancer based on single-cell RNA sequencing
por: Xue, Qianqian, et al.
Publicado: (2023)

Pan-Cancer Analysis Reveals the Signature of TMC Family of Genes as a Promising Biomarker for Prognosis and Immunotherapeutic Response
por: Song, Jing, et al.
Publicado: (2021)

Immune-related long non-coding RNA signature identified prognosis and immunotherapeutic efficiency in bladder cancer (BLCA)
por: Cao, Rui, et al.
Publicado: (2020)

Machine-learning based integrating bulk and single-cell RNA sequencing reveals the SLC38A5-CCL5 signaling as a promising target for clear cell renal cell carcinoma treatment
por: Chen, Hualin, et al.
Publicado: (2023)

Immunotherapeutic Significance of a Prognostic Alternative Splicing Signature in Bladder Cancer
por: Chen, Jiang, et al.
Publicado: (2022)

Detailed bladder cancer immunoprofiling reveals new clues for immunotherapeutic strategies
por: Viveiros, Nicole, et al.
Publicado: (2022)

Construction and experimental validation of a B cell-related gene signature to predict the prognosis and immunotherapeutic sensitivity in bladder cancer
por: Zhou, Ranran, et al.
Publicado: (2023)

TTN/OBSCN ‘Double‐Hit’ predicts favourable prognosis, ‘immune‐hot’ subtype and potentially better immunotherapeutic efficacy in colorectal cancer
por: Liu, Zaoqu, et al.
Publicado: (2021)

Comprehensive analysis of the prognostic and immunotherapeutic implications of STAT family members in human colorectal cancer
por: Li, Dingchang, et al.
Publicado: (2022)

Transcriptome sequencing and single-cell sequencing analysis identify GARS1 as a potential prognostic and immunotherapeutic biomarker for multiple cancers, including bladder cancer
por: Nie, Jianqiang, et al.
Publicado: (2023)

Identification of Cancer-Associated Fibroblast Subtype of Triple-Negative Breast Cancer
por: Wang, Maoli, et al.
Publicado: (2022)

Identification of cuproptosis-related lncRNA for predicting prognosis and immunotherapeutic response in cervical cancer
por: Kong, Xiaoyu, et al.
Publicado: (2023)

Tumor-Infiltrating B Lymphocytes: Promising Immunotherapeutic Targets for Primary Liver Cancer Treatment
por: Milardi, Giulia, et al.
Publicado: (2023)

Stromal infiltrating mast cells identify immunoevasive subtype high-grade serous ovarian cancer with poor prognosis and inferior immunotherapeutic response
por: Cao, Kankan, et al.
Publicado: (2021)

Promising Immunotherapeutic Modalities for B-Cell Lymphoproliferative Disorders
por: Mihályová, Jana, et al.
Publicado: (2021)

Treg: A Promising Immunotherapeutic Target in Oral Diseases
por: Zhang, Yujing, et al.
Publicado: (2021)

Identification of cancer-associated fibroblasts subtypes in prostate cancer
por: Pan, Jiahua, et al.
Publicado: (2023)

Colorectal Cancer Immune Infiltrates: Significance in Patient Prognosis and Immunotherapeutic Efficacy
por: Guo, Liang, et al.
Publicado: (2020)

Cuproplasia characterization in colon cancer assists to predict prognosis and immunotherapeutic response
por: Zhang, Bomiao, et al.
Publicado: (2023)

Inflammatory Pathways as Promising Targets to Increase Chemotherapy Response in Bladder Cancer
por: Zhu, Zhaowei, et al.
Publicado: (2012)

Identification of immune subtypes and their prognosis and molecular implications in colorectal cancer
por: Sun, Yan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_g4rphnouhp6b6n1dr54utumolr