High-Resolution Splenic Imaging: [(68)Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma

The differentiation of splenic tissue from malignant lesions via imaging may be challenging, particularly considering aberrant or accessory lesions and diseases that are rarely encountered. Functioning splenic tissue can be identified using technetium-99m red blood cell ((99m)Tc-RBC) scintigraphy, b...

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Autores principales: Werner, Anke, Freesmeyer, Martin, Drescher, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781823/
https://www.ncbi.nlm.nih.gov/pubmed/36548536
http://dx.doi.org/10.3390/tomography8060244
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author Werner, Anke
Freesmeyer, Martin
Drescher, Robert
author_facet Werner, Anke
Freesmeyer, Martin
Drescher, Robert
author_sort Werner, Anke
collection PubMed
description The differentiation of splenic tissue from malignant lesions via imaging may be challenging, particularly considering aberrant or accessory lesions and diseases that are rarely encountered. Functioning splenic tissue can be identified using technetium-99m red blood cell ((99m)Tc-RBC) scintigraphy, but its sensitivity is limited and may not be available. We present the case of a patient in whom disseminated abdomino-pelvic splenosis was diagnosed using PET/CT with gallium-68-oxine-labeled RBCs. The method represents a feasible and probably superior alternative to splenic scintigraphy.
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spelling pubmed-97818232022-12-24 High-Resolution Splenic Imaging: [(68)Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma Werner, Anke Freesmeyer, Martin Drescher, Robert Tomography Case Report The differentiation of splenic tissue from malignant lesions via imaging may be challenging, particularly considering aberrant or accessory lesions and diseases that are rarely encountered. Functioning splenic tissue can be identified using technetium-99m red blood cell ((99m)Tc-RBC) scintigraphy, but its sensitivity is limited and may not be available. We present the case of a patient in whom disseminated abdomino-pelvic splenosis was diagnosed using PET/CT with gallium-68-oxine-labeled RBCs. The method represents a feasible and probably superior alternative to splenic scintigraphy. MDPI 2022-12-12 /pmc/articles/PMC9781823/ /pubmed/36548536 http://dx.doi.org/10.3390/tomography8060244 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Werner, Anke
Freesmeyer, Martin
Drescher, Robert
High-Resolution Splenic Imaging: [(68)Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma
title High-Resolution Splenic Imaging: [(68)Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma
title_full High-Resolution Splenic Imaging: [(68)Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma
title_fullStr High-Resolution Splenic Imaging: [(68)Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma
title_full_unstemmed High-Resolution Splenic Imaging: [(68)Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma
title_short High-Resolution Splenic Imaging: [(68)Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma
title_sort high-resolution splenic imaging: [(68)ga]ga-oxine red blood cell pet/ct for differentiation of splenosis mimicking malignant lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781823/
https://www.ncbi.nlm.nih.gov/pubmed/36548536
http://dx.doi.org/10.3390/tomography8060244
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