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Long-Term Follow-Up of Lower Urinary Tract Outcome in Children with Dysfunctional Voiding

Objective: To investigate the long-term clinical and urodynamic outcomes of a small cohort of children who received short-term urotherapy for confirmed dysfunctional voiding (DV) and lower urinary tract symptoms (LUTS). Materials and Methods: This study included 26 children with confirmed LUTS and D...

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Autores principales: Peng, Chung-Hsin, Chen, Sheng-Fu, Kuo, Hann-Chorng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781924/
https://www.ncbi.nlm.nih.gov/pubmed/36556011
http://dx.doi.org/10.3390/jcm11247395
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author Peng, Chung-Hsin
Chen, Sheng-Fu
Kuo, Hann-Chorng
author_facet Peng, Chung-Hsin
Chen, Sheng-Fu
Kuo, Hann-Chorng
author_sort Peng, Chung-Hsin
collection PubMed
description Objective: To investigate the long-term clinical and urodynamic outcomes of a small cohort of children who received short-term urotherapy for confirmed dysfunctional voiding (DV) and lower urinary tract symptoms (LUTS). Materials and Methods: This study included 26 children with confirmed LUTS and DV via video urodynamic study (VUDS) and received standard urological therapy, pelvic floor muscle training, or surgical intervention in childhood. Their current lower urinary tract conditions were assessed by chart review and direct and telephone interviews. Charts of 14 patients who underwent follow-up VUDS were reviewed to investigate their bladder and voiding dysfunction or follow-up on previous treatment results. The satisfaction of lower urinary tract status was assessed using the global response assessment (GRA) scale. Results: At initial enrolment, the mean age was 9.54 ± 3.88 years, and urological treatment was performed during the first 1–5 years thereafter. Most patients were not regularly followed in the urology clinic. Among the 14 children available for follow-up, a GRA score of 3 was reported by 10 (71.4%) after a mean follow-up period of 10.3 ± 6.74 (range, 2–20) years, indicating satisfactory bladder and voiding conditions. Four children with less favorable outcomes (GRA score of <3) had significantly more post-void residual urine volume at baseline, and 75% of these patients had central nervous system diseases. Daytime incontinence and enuresis rates were significantly decreased at follow-up compared with the baseline. Significantly increased bladder capacity and sensation and significantly decreased voiding detrusor pressure were found on follow-up VUDS. Conclusions: Children with DV who received standard urotherapy upon diagnosis exhibited improved LUTS at a 10-year follow-up. Of the 14 children available for follow-up, 10 (71.4%) reported satisfactory bladder and voiding status without further medication or urotherapy, with significantly decreased voiding detrusor pressure.
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spelling pubmed-97819242022-12-24 Long-Term Follow-Up of Lower Urinary Tract Outcome in Children with Dysfunctional Voiding Peng, Chung-Hsin Chen, Sheng-Fu Kuo, Hann-Chorng J Clin Med Article Objective: To investigate the long-term clinical and urodynamic outcomes of a small cohort of children who received short-term urotherapy for confirmed dysfunctional voiding (DV) and lower urinary tract symptoms (LUTS). Materials and Methods: This study included 26 children with confirmed LUTS and DV via video urodynamic study (VUDS) and received standard urological therapy, pelvic floor muscle training, or surgical intervention in childhood. Their current lower urinary tract conditions were assessed by chart review and direct and telephone interviews. Charts of 14 patients who underwent follow-up VUDS were reviewed to investigate their bladder and voiding dysfunction or follow-up on previous treatment results. The satisfaction of lower urinary tract status was assessed using the global response assessment (GRA) scale. Results: At initial enrolment, the mean age was 9.54 ± 3.88 years, and urological treatment was performed during the first 1–5 years thereafter. Most patients were not regularly followed in the urology clinic. Among the 14 children available for follow-up, a GRA score of 3 was reported by 10 (71.4%) after a mean follow-up period of 10.3 ± 6.74 (range, 2–20) years, indicating satisfactory bladder and voiding conditions. Four children with less favorable outcomes (GRA score of <3) had significantly more post-void residual urine volume at baseline, and 75% of these patients had central nervous system diseases. Daytime incontinence and enuresis rates were significantly decreased at follow-up compared with the baseline. Significantly increased bladder capacity and sensation and significantly decreased voiding detrusor pressure were found on follow-up VUDS. Conclusions: Children with DV who received standard urotherapy upon diagnosis exhibited improved LUTS at a 10-year follow-up. Of the 14 children available for follow-up, 10 (71.4%) reported satisfactory bladder and voiding status without further medication or urotherapy, with significantly decreased voiding detrusor pressure. MDPI 2022-12-13 /pmc/articles/PMC9781924/ /pubmed/36556011 http://dx.doi.org/10.3390/jcm11247395 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Peng, Chung-Hsin
Chen, Sheng-Fu
Kuo, Hann-Chorng
Long-Term Follow-Up of Lower Urinary Tract Outcome in Children with Dysfunctional Voiding
title Long-Term Follow-Up of Lower Urinary Tract Outcome in Children with Dysfunctional Voiding
title_full Long-Term Follow-Up of Lower Urinary Tract Outcome in Children with Dysfunctional Voiding
title_fullStr Long-Term Follow-Up of Lower Urinary Tract Outcome in Children with Dysfunctional Voiding
title_full_unstemmed Long-Term Follow-Up of Lower Urinary Tract Outcome in Children with Dysfunctional Voiding
title_short Long-Term Follow-Up of Lower Urinary Tract Outcome in Children with Dysfunctional Voiding
title_sort long-term follow-up of lower urinary tract outcome in children with dysfunctional voiding
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781924/
https://www.ncbi.nlm.nih.gov/pubmed/36556011
http://dx.doi.org/10.3390/jcm11247395
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