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Treatment of Complex Wounds with NovoSorb(®) Biodegradable Temporising Matrix (BTM)—A Retrospective Analysis of Clinical Outcomes

Complex and chronic wounds represent a highly prevalent condition worldwide that requires a multimodal and interdisciplinary treatment approach to achieve good functional and aesthetic outcomes. Due to increasing costs of health care, an aging population and an increase in difficult-to-treat microbi...

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Autores principales: Schlottmann, Frederik, Obed, Doha, Bingöl, Alperen S., März, Vincent, Vogt, Peter M., Krezdorn, Nicco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781929/
https://www.ncbi.nlm.nih.gov/pubmed/36556223
http://dx.doi.org/10.3390/jpm12122002
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author Schlottmann, Frederik
Obed, Doha
Bingöl, Alperen S.
März, Vincent
Vogt, Peter M.
Krezdorn, Nicco
author_facet Schlottmann, Frederik
Obed, Doha
Bingöl, Alperen S.
März, Vincent
Vogt, Peter M.
Krezdorn, Nicco
author_sort Schlottmann, Frederik
collection PubMed
description Complex and chronic wounds represent a highly prevalent condition worldwide that requires a multimodal and interdisciplinary treatment approach to achieve good functional and aesthetic outcomes. Due to increasing costs of health care, an aging population and an increase in difficult-to-treat microbial colonization of wounds, complex wounds will become a substantial clinical, social and economic challenge in the upcoming years. In plastic reconstructive surgery, a variety of dermal skin substitutes have been established for clinical use. Since its approval as a dermal skin substitute in Germany, NovoSorb(®) Biodegradable Temporising Matrix (BTM) has become a valuable therapeutic option for the treatment of full-thickness wound defects. The clinical data published to date are limited to case reports and small-scale case series with the main focus on single wounds. The aim of this single-center study was a retrospective analysis of our own patient collective that has received treatment with BTM for complex wounds. Overall, BTM showed to be a reliable and versatile reconstructive option, especially for patients with multiple co-morbidities and microbiologically colonized wounds. Although the preliminary findings have produced promising results, further investigation and research are warranted regarding long-term outcomes and additional clinical applications.
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spelling pubmed-97819292022-12-24 Treatment of Complex Wounds with NovoSorb(®) Biodegradable Temporising Matrix (BTM)—A Retrospective Analysis of Clinical Outcomes Schlottmann, Frederik Obed, Doha Bingöl, Alperen S. März, Vincent Vogt, Peter M. Krezdorn, Nicco J Pers Med Article Complex and chronic wounds represent a highly prevalent condition worldwide that requires a multimodal and interdisciplinary treatment approach to achieve good functional and aesthetic outcomes. Due to increasing costs of health care, an aging population and an increase in difficult-to-treat microbial colonization of wounds, complex wounds will become a substantial clinical, social and economic challenge in the upcoming years. In plastic reconstructive surgery, a variety of dermal skin substitutes have been established for clinical use. Since its approval as a dermal skin substitute in Germany, NovoSorb(®) Biodegradable Temporising Matrix (BTM) has become a valuable therapeutic option for the treatment of full-thickness wound defects. The clinical data published to date are limited to case reports and small-scale case series with the main focus on single wounds. The aim of this single-center study was a retrospective analysis of our own patient collective that has received treatment with BTM for complex wounds. Overall, BTM showed to be a reliable and versatile reconstructive option, especially for patients with multiple co-morbidities and microbiologically colonized wounds. Although the preliminary findings have produced promising results, further investigation and research are warranted regarding long-term outcomes and additional clinical applications. MDPI 2022-12-03 /pmc/articles/PMC9781929/ /pubmed/36556223 http://dx.doi.org/10.3390/jpm12122002 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Schlottmann, Frederik
Obed, Doha
Bingöl, Alperen S.
März, Vincent
Vogt, Peter M.
Krezdorn, Nicco
Treatment of Complex Wounds with NovoSorb(®) Biodegradable Temporising Matrix (BTM)—A Retrospective Analysis of Clinical Outcomes
title Treatment of Complex Wounds with NovoSorb(®) Biodegradable Temporising Matrix (BTM)—A Retrospective Analysis of Clinical Outcomes
title_full Treatment of Complex Wounds with NovoSorb(®) Biodegradable Temporising Matrix (BTM)—A Retrospective Analysis of Clinical Outcomes
title_fullStr Treatment of Complex Wounds with NovoSorb(®) Biodegradable Temporising Matrix (BTM)—A Retrospective Analysis of Clinical Outcomes
title_full_unstemmed Treatment of Complex Wounds with NovoSorb(®) Biodegradable Temporising Matrix (BTM)—A Retrospective Analysis of Clinical Outcomes
title_short Treatment of Complex Wounds with NovoSorb(®) Biodegradable Temporising Matrix (BTM)—A Retrospective Analysis of Clinical Outcomes
title_sort treatment of complex wounds with novosorb(®) biodegradable temporising matrix (btm)—a retrospective analysis of clinical outcomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781929/
https://www.ncbi.nlm.nih.gov/pubmed/36556223
http://dx.doi.org/10.3390/jpm12122002
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