Piracetam as a Therapeutic Agent for Doxorubicin-Induced Cognitive Deficits by Enhancing Cholinergic Functions and Reducing Neuronal Inflammation, Apoptosis, and Oxidative Stress in Rats

Cancer chemotherapy is known to cause cognitive defects in patients. Our study investigated the effect of piracetam (PIRA; 200 or 400 mg/kg) against doxorubicin (DOX)-induced cognitive deficits in a rat model. The cognitive parameters were analyzed using elevated plus-maze, novel object recognition,...

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Detalles Bibliográficos
Autores principales: Mani, Vasudevan, Rabbani, Syed Imam, Shariq, Ali, Amirthalingam, Palanisamy, Arfeen, Minhajul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781976/
https://www.ncbi.nlm.nih.gov/pubmed/36559014
http://dx.doi.org/10.3390/ph15121563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781976/
https://www.ncbi.nlm.nih.gov/pubmed/36559014
http://dx.doi.org/10.3390/ph15121563

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