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ANN-Based Instantaneous Simulation of Particle Trajectories in Microfluidics

Microfluidics has shown great potential in cell analysis, where the flowing path in the microfluidic device is important for the final study results. However, the design process is time-consuming and labor-intensive. Therefore, we proposed an ANN method with three dense layers to analyze particle tr...

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Detalles Bibliográficos
Autores principales: Zhang, Naiyin, Liang, Kaicong, Liu, Zhenya, Sun, Taotao, Wang, Junchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781979/
https://www.ncbi.nlm.nih.gov/pubmed/36557399
http://dx.doi.org/10.3390/mi13122100
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author Zhang, Naiyin
Liang, Kaicong
Liu, Zhenya
Sun, Taotao
Wang, Junchao
author_facet Zhang, Naiyin
Liang, Kaicong
Liu, Zhenya
Sun, Taotao
Wang, Junchao
author_sort Zhang, Naiyin
collection PubMed
description Microfluidics has shown great potential in cell analysis, where the flowing path in the microfluidic device is important for the final study results. However, the design process is time-consuming and labor-intensive. Therefore, we proposed an ANN method with three dense layers to analyze particle trajectories at the critical intersections and then put them together with the particle trajectories in straight channels. The results showed that the ANN prediction results are highly consistent with COMSOL simulation results, indicating the applicability of the proposed ANN method. In addition, this method not only shortened the simulation time but also lowered the computational expense, providing a useful tool for researchers who want to receive instant simulation results of particle trajectories.
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spelling pubmed-97819792022-12-24 ANN-Based Instantaneous Simulation of Particle Trajectories in Microfluidics Zhang, Naiyin Liang, Kaicong Liu, Zhenya Sun, Taotao Wang, Junchao Micromachines (Basel) Article Microfluidics has shown great potential in cell analysis, where the flowing path in the microfluidic device is important for the final study results. However, the design process is time-consuming and labor-intensive. Therefore, we proposed an ANN method with three dense layers to analyze particle trajectories at the critical intersections and then put them together with the particle trajectories in straight channels. The results showed that the ANN prediction results are highly consistent with COMSOL simulation results, indicating the applicability of the proposed ANN method. In addition, this method not only shortened the simulation time but also lowered the computational expense, providing a useful tool for researchers who want to receive instant simulation results of particle trajectories. MDPI 2022-11-28 /pmc/articles/PMC9781979/ /pubmed/36557399 http://dx.doi.org/10.3390/mi13122100 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Naiyin
Liang, Kaicong
Liu, Zhenya
Sun, Taotao
Wang, Junchao
ANN-Based Instantaneous Simulation of Particle Trajectories in Microfluidics
title ANN-Based Instantaneous Simulation of Particle Trajectories in Microfluidics
title_full ANN-Based Instantaneous Simulation of Particle Trajectories in Microfluidics
title_fullStr ANN-Based Instantaneous Simulation of Particle Trajectories in Microfluidics
title_full_unstemmed ANN-Based Instantaneous Simulation of Particle Trajectories in Microfluidics
title_short ANN-Based Instantaneous Simulation of Particle Trajectories in Microfluidics
title_sort ann-based instantaneous simulation of particle trajectories in microfluidics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781979/
https://www.ncbi.nlm.nih.gov/pubmed/36557399
http://dx.doi.org/10.3390/mi13122100
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AT suntaotao annbasedinstantaneoussimulationofparticletrajectoriesinmicrofluidics
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