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Dolutegravir Discontinuation for Neuropsychiatric Symptoms in People Living with HIV and Their Outcomes after Treatment Change: A Pharmacogenetic Study
Neuropsychiatric symptoms have been reported in patients receiving dolutegravir, a known inhibitor of the renal and neuronal-expressed organic anion transporter 2 (encoded by SLC22A2 gene). The effect of the genetic variant SLC22A2 808C>A on dolutegravir discontinuation was assessed and analyzed...
Autores principales: | Cusato, Jessica, Borghetti, Alberto, Teti, Elisabetta, Milesi, Maurizio, Tettoni, Maria Cristina, Bonora, Stefano, Trunfio, Mattia, D’Avolio, Antonio, Compagno, Mirko, Di Giambenedetto, Simona, Di Perri, Giovanni, Calcagno, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9781993/ https://www.ncbi.nlm.nih.gov/pubmed/36557240 http://dx.doi.org/10.3390/metabo12121202 |
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