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Practical Recommendations for the Manipulation of Kinase Inhibitor Formulations to Age-Appropriate Dosage Forms

Over 75 kinase inhibitors (KIs) have been approved for the treatment of various cancers. KIs are orally administrated but mostly lack pediatric age-appropriate dosage forms or instructions for dose manipulation. This is highly problematic for clinical practice in pediatric oncology, as flexible oral...

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Detalles Bibliográficos
Autores principales:	Bernsen, Emma C., Hogenes, Valery J., Nuijen, Bastiaan, Hanff, Lidwien M., Huitema, Alwin D. R., Diekstra, Meta H. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782008/ https://www.ncbi.nlm.nih.gov/pubmed/36559327 http://dx.doi.org/10.3390/pharmaceutics14122834

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