Cargando…
Optimisation of a High-Throughput Model for Mucus Permeation and Nanoparticle Discrimination Using Biosimilar Mucus
High-throughput permeation models are essential in drug development for timely screening of new drug and formulation candidates. Nevertheless, many current permeability assays fail to account for the presence of the gastrointestinal mucus layer. In this study, an optimised high-throughput mucus perm...
Autores principales: | Wright, Leah, Barnes, Timothy J., Joyce, Paul, Prestidge, Clive A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782027/ https://www.ncbi.nlm.nih.gov/pubmed/36559151 http://dx.doi.org/10.3390/pharmaceutics14122659 |
Ejemplares similares
-
Peptide-Mucin Binding and Biosimilar Mucus-Permeating Properties
por: Sun, Xiaohong, et al.
Publicado: (2021) -
Mimicking microbial strategies for the design of mucus-permeating nanoparticles for oral immunization
por: Gamazo, Carlos, et al.
Publicado: (2015) -
Mucus
por: Cutler, Andrew S.
Publicado: (1868) -
Altering Mucus Rheology to “Solidify” Human Mucus at the Nanoscale
por: Lai, Samuel K., et al.
Publicado: (2009) -
Optical catapulting of microspheres in mucus models—toward overcoming the mucus biobarrier
por: Bunea, Ada-Ioana, et al.
Publicado: (2019)