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Optimisation of a High-Throughput Model for Mucus Permeation and Nanoparticle Discrimination Using Biosimilar Mucus

High-throughput permeation models are essential in drug development for timely screening of new drug and formulation candidates. Nevertheless, many current permeability assays fail to account for the presence of the gastrointestinal mucus layer. In this study, an optimised high-throughput mucus perm...

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Detalles Bibliográficos
Autores principales: Wright, Leah, Barnes, Timothy J., Joyce, Paul, Prestidge, Clive A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782027/
https://www.ncbi.nlm.nih.gov/pubmed/36559151
http://dx.doi.org/10.3390/pharmaceutics14122659

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