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CRISPR-Cas Controls Cryptic Prophages

The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages. Specifically, compared to the wi...

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Detalles Bibliográficos
Autores principales:	Song, Sooyeon, Semenova, Ekaterina, Severinov, Konstantin, Fernández-García, Laura, Benedik, Michael J., Maeda, Toshinari, Wood, Thomas K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782134/ https://www.ncbi.nlm.nih.gov/pubmed/36555835 http://dx.doi.org/10.3390/ijms232416195

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