Target Identification of 22-(4-Pyridinecarbonyl) Jorunnamycin A, a Tetrahydroisoquinoline Derivative from the Sponge Xestospongia sp., in Mediating Non-Small-Cell Lung Cancer Cell Apoptosis

A dysregulation of the cell-death mechanism contributes to poor prognosis in lung cancer. New potent chemotherapeutic agents targeting apoptosis-deregulating molecules have been discovered. In this study, 22-(4-pyridinecarbonyl) jorunnamycin A (22-(4′py)-JA), a synthetic derivative of bistetrahydroi...

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Detalles Bibliográficos
Autores principales: Iksen, Iksen, Sinsook, Suwimon, Wattanathamsan, Onsurang, Buaban, Koonchira, Chamni, Supakarn, Pongrakhananon, Varisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782168/
https://www.ncbi.nlm.nih.gov/pubmed/36558080
http://dx.doi.org/10.3390/molecules27248948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782168/
https://www.ncbi.nlm.nih.gov/pubmed/36558080
http://dx.doi.org/10.3390/molecules27248948

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