Observation of α-Synuclein Preformed Fibrils Interacting with SH-SY5Y Neuroblastoma Cell Membranes Using Scanning Ion Conductance Microscopy

[Image: see text] Parkinson’s disease (PD) is the second-most prevalent neurodegenerative disorder in the U.S. α-Synuclein (α-Syn) preformed fibrils (PFFs) have been shown to propagate PD pathology in neuronal populations. However, little work has directly characterized the morphological changes on...

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Detalles Bibliográficos
Autores principales: Feng, Christina, Flores, Marisol, Dhoj, Christina, Garcia, Adaly, Belleca, Sheehan, Abbas, Dana Abou, Parres-Gold, Jacob, Anguiano, Aimee, Porter, Edith, Wang, Yixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782390/
https://www.ncbi.nlm.nih.gov/pubmed/36455298
http://dx.doi.org/10.1021/acschemneuro.2c00478

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