Cargando…

N,2,6-Trisubstituted 1H-benzimidazole derivatives as a new scaffold of antimicrobial and anticancer agents: design, synthesis, in vitro evaluation, and in silico studies

Compounds containing benzimidazole moiety occupy privileged chemical space for discovering new bioactive substances. In continuation of our recent work, 69 benzimidazole derivatives were designed and synthesized with good to excellent yields of 46–99% using efficient synthesis protocol i.e. sodium m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pham, Em Canh, Le Thi, Tuong Vi, Ly Hong, Huong Ha, Vo Thi, Bich Ngoc, Vong, Long B., Vu, Thao Thanh, Vo, Duy Duc, Tran Nguyen, Ngoc Vi, Bao Le, Khanh Nguyen, Truong, Tuyen Ngoc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782508/ https://www.ncbi.nlm.nih.gov/pubmed/36605630 http://dx.doi.org/10.1039/d2ra06667j

Ejemplares similares

Design, synthesis, bio-evaluation, and in silico studies of some N-substituted 6-(chloro/nitro)-1H-benzimidazole derivatives as antimicrobial and anticancer agents
por: Pham, Em Canh, et al.
Publicado: (2022)

Descending Thoracic Aorta Stenosis Treated by Percutaneous Transluminal Angioplasty and Stenting with Coaxial Sheath Introduction Technique in a Small Child
por: Ho Anh, Binh, et al.
Publicado: (2021)

Eye and renal complication in pediatric patients with diabetes mellitus type 1
por: Hieu, Nguyen Tran Ngoc, et al.
Publicado: (2015)

Response of Lactobacillus plantarum VAL6 to challenges of pH and sodium chloride stresses
por: Nguyen, Phu-Tho, et al.
Publicado: (2021)

HIV Prevalence and Factors Related to HIV Infection Among Transgender Women in Vietnam: A Respondent Driven Sampling Approach
por: Vi, Vu Thi Tuong, et al.
Publicado: (2020)

Study relationship between the value of 17-OHP and the value of testosterone in monitoring for congenital adrenal hyperplasia
por: Huong, Ngo Thi Thu, et al.
Publicado: (2013)

An efficient multicomponent synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles catalyzed by a magnetic nanoparticle supported Lewis acidic deep eutectic solvent
por: Nguyen, Thanh Thi, et al.
Publicado: (2019)

Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding: A case report
por: Nguyen, Long Cong, et al.
Publicado: (2021)

Correction: An efficient multicomponent synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles catalyzed by a magnetic nanoparticle supported Lewis acidic deep eutectic solvent
por: Nguyen, Thanh Thi, et al.
Publicado: (2020)

Multiple endocrine glands insufficiency due to langerhans cell histiocytosis (LCH): a case report
por: Mai, DoThi Thanh, et al.
Publicado: (2015)

Congenital adrenal hyperplasia with cholestatic jaundice: a case report
por: Mai, DoThi Thanh, et al.
Publicado: (2015)

Hypopituitarism due to central nervous system germinoma: a case report
por: Mai, DoThi Thanh, et al.
Publicado: (2015)

Adrenal cortex tumors: clinical features and laboratory finding
por: Ngoc, Can Thi Bich, et al.
Publicado: (2013)

Cushing's syndrome due to atypical carcinoid of the mediastinum
por: Nga, Vu Bich, et al.
Publicado: (2023)

Mixed embryonal carcinoma – teratoma cause early puberty: a case report
por: Ngoc, Can Thi Bich, et al.
Publicado: (2015)

Effectiveness of educational intervention carried out by clinical pharmacists for the quality of life of patients with irritable bowel syndrome: A randomized controlled trial
por: Thong, Vo Duy, et al.
Publicado: (2020)

Effect of Pharmacist-Led Interventions on Medication Adherence among Vietnamese Patients with Asthma: A Randomized Controlled Trial
por: Nguyen, Tan Thanh, et al.
Publicado: (2023)

An Update on Anti-CD137 Antibodies in Immunotherapies for Cancer
por: Chu, Dinh-Toi, et al.
Publicado: (2019)

Normative data for the Vietnamese smell identification test
por: Tran, Tai Ngoc, et al.
Publicado: (2023)

Primary hyperlipidemia in children: clinical, biochemistry characteristics and outcome
por: Khanh, Nguyen Ngoc, et al.
Publicado: (2015)

Adherence to Social Distancing Measures for Controlling COVID-19 Pandemic: Successful Lesson From Vietnam
por: Vo, Hoang-Long, et al.
Publicado: (2020)

Gelatin/carboxymethyl cellulose edible films: modification of physical properties by different hydrocolloids and application in beef preservation in combination with shallot waste powder
por: Tran, Thi Tuong Vi, et al.
Publicado: (2023)

Clinical Epidemiology Characteristics and Etiology of Febrile Neutropenia in Children: Analysis of 421 Cases
por: Nguyen, Sang Ngoc, et al.
Publicado: (2022)

Examining financial distress of the Vietnamese listed firms using accounting-based models
por: Tran, Thao, et al.
Publicado: (2023)

Design, Microwave-Assisted Synthesis, Antimicrobial and Anticancer Evaluation, and In Silico Studies of Some 2-Naphthamide Derivatives as DHFR and VEGFR-2 Inhibitors
por: Canh Pham, Em, et al.
Publicado: (2022)

Phenotype and genotype of patients with disorder of sex development due to 5α-reductase deficiency
por: Dung, Vu Chi, et al.
Publicado: (2015)

Updated registry of congenital adrenal hyperplasia at the north pediatric referral centre of Vietnam
por: Dung, Vu Chi, et al.
Publicado: (2015)

Health and Economic Benefits of Air Pollution Reductions in Vietnam During 2020–2021
por: Hoang, Le Tu, et al.
Publicado: (2023)

Fabrication of Silver Nanoparticles Using Cordyline fruticosa L. Leave Extract Endowing Silk Fibroin Modified Viscose Fabric with Durable Antibacterial Property
por: Nguyen, Ngoc-Thang, et al.
Publicado: (2022)

Determination of the Assigned Values of Blood Cells by an Impedance Method for Hematological Reference Samples Used in Hematology External Quality Assessment (EQA) Programs
por: Vo, Ngoc Nguyen, et al.
Publicado: (2022)

Mutations of ABCD1 gene and phenotype of Vietnamese patients with X-linked adrenoleukodystrophy (X-ALD)
por: Dung, Vu Chi, et al.
Publicado: (2013)

Phenotype & genotype of congenital adrenal hyperplasia due to mutation in the type ii 3β-hydroxysteroid dehydrogenase gene: a report of two Vietnamese families
por: Dung, Vu Chi, et al.
Publicado: (2015)

Anatomical Characteristics of Thalamus-Cortical Sensory Tract in the Human Brain Using Diffusion Tensor Tractography at 3.0 Tesla Scanner
por: Khanh, Lam, et al.
Publicado: (2019)

Microscopic Observation Drug Susceptibility Assay (MODS) for Early Diagnosis of Tuberculosis in Children
por: Ha, Dang Thi Minh, et al.
Publicado: (2009)

Molecular genetics and phenotype of 26 Vietnamese patients with congenital hyperinsulinism
por: Dung, Vu Chi, et al.
Publicado: (2013)

Insights into Structural, Electronic, and Transport Properties of Pentagonal PdSe(2) Nanotubes Using First-Principles Calculations
por: Tien, Nguyen Thanh, et al.
Publicado: (2023)

Quality of life and health status of hospitalized adults with congenital heart disease in Vietnam: a cross-sectional study
por: Truong, Thanh-Huong, et al.
Publicado: (2021)

A cross-sectional study on the Nesfatin-1 serum levels of Vietnamese patients with pre-diabetes
por: Duc, Nguyen Minh, et al.
Publicado: (2023)

Essential Oils of Zingiber Species from Vietnam: Chemical Compositions and Biological Activities
por: Huong, Le Thi, et al.
Publicado: (2020)

Treatment outcome and some affecting factors of congenital adrenalhyperplasia
por: Dat, Nguyen Phu, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_e1iiosgc2ka5agm9m8fevg3lod