Spray-Dried Inhalable Powder Formulations of Gentamicin Designed for Pneumonic Plague Therapy in a Mouse Model

Infection with Yersinia pestis (Y. pestis) may cause pneumonic plague, which is inevitably fatal without treatment. Gentamicin (GM), an aminoglycoside antibiotic, is a drug commonly used in the treatment of plague. However, it requires repeated intramuscular or intravenous administration. Pulmonary...

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Detalles Bibliográficos
Autores principales: Zhu, Menghuan, Zhang, Dongna, Zhang, Lili, Zhao, Liangliang, Xu, Likun, Wang, Baogang, Zhang, Xinyu, Chen, Jinwei, Bei, Zhuchun, Wang, Hong, Zhou, Dongsheng, Yang, Wenhui, Song, Yabin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782578/
https://www.ncbi.nlm.nih.gov/pubmed/36559140
http://dx.doi.org/10.3390/pharmaceutics14122646

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