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3,6-dichlorobenzo[b]thiophene-2-carboxylic acid alleviates ulcerative colitis by suppressing mammalian target of rapamycin complex 1 activation and regulating intestinal microbiota

BACKGROUND: 3,6-dichlorobenzo[b]thiophene-2-carboxylic acid (BT2) is a benzothiophene carboxylate derivative that can suppress the catabolism of branched-chain amino acid (BCAA)-associated mammalian target of rapamycin complex 1 (mTORC1) activation. Previous studies have demonstrated the therapeutic...

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Detalles Bibliográficos
Autores principales:	He, Qiong-Zi, Wei, Peng, Zhang, Jun-Zhi, Liu, Tong-Tong, Shi, Kun-Qun, Liu, Huan-Huan, Zhang, Jing-Wei, Liu, Shi-Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2022
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782837/ https://www.ncbi.nlm.nih.gov/pubmed/36569276 http://dx.doi.org/10.3748/wjg.v28.i46.6522

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