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Resveratrol Inhibits Oxidative Stress and Regulates M1/M2-Type Polarization of Microglia via Mediation of the Nrf2/Shh Signaling Cascade after OGD/R Injury In Vitro
Aims: Microglia are closely related to the occurrence and development of oxidative stress. Cerebral ischemia leads to abnormal activation of microglia. Resveratrol can regulate M1/M2-type microglia polarization, but the underlying mechanism is not well understood, although the Nrf2 and Shh signaling...
Autores principales: | Liu, Jie, Liao, Hongyan, Chen, Yue, Zhu, Huimin, Li, Xuemei, Liu, Jing, Xiang, Qin, Zeng, Fanling, Yang, Qin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782981/ https://www.ncbi.nlm.nih.gov/pubmed/36556306 http://dx.doi.org/10.3390/jpm12122087 |
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