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Polysaccharide-Based Nanomedicines Targeting Lung Cancer
A primary illness that accounts for a significant portion of fatalities worldwide is cancer. Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer around the globe. Radiation treatment, surgery, and chemotherapy are some medical procedures used in the traditional...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782996/ https://www.ncbi.nlm.nih.gov/pubmed/36559281 http://dx.doi.org/10.3390/pharmaceutics14122788 |
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author | Bhat, Asif Ahmad Gupta, Gaurav Alharbi, Khalid Saad Afzal, Obaid Altamimi, Abdulmalik S. A. Almalki, Waleed Hassan Kazmi, Imran Al-Abbasi, Fahad A. Alzarea, Sami I. Chellappan, Dinesh Kumar Singh, Sachin Kumar MacLoughlin, Ronan Oliver, Brian G Dua, Kamal |
author_facet | Bhat, Asif Ahmad Gupta, Gaurav Alharbi, Khalid Saad Afzal, Obaid Altamimi, Abdulmalik S. A. Almalki, Waleed Hassan Kazmi, Imran Al-Abbasi, Fahad A. Alzarea, Sami I. Chellappan, Dinesh Kumar Singh, Sachin Kumar MacLoughlin, Ronan Oliver, Brian G Dua, Kamal |
author_sort | Bhat, Asif Ahmad |
collection | PubMed |
description | A primary illness that accounts for a significant portion of fatalities worldwide is cancer. Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer around the globe. Radiation treatment, surgery, and chemotherapy are some medical procedures used in the traditional care of lung cancer. However, these methods lack selectivity and damage nearby healthy cells. Several polysaccharide-based nanomaterials have been created to transport chemotherapeutics to reduce harmful and adverse side effects and improve response during anti-tumour reactions. To address these drawbacks, a class of naturally occurring polymers called polysaccharides have special physical, chemical, and biological characteristics. They can interact with the immune system to induce a better immunological response. Furthermore, because of the flexibility of their structures, it is possible to create multifunctional nanocomposites with excellent stability and bioavailability for the delivery of medicines to tumour tissues. This study seeks to present new views on the use of polysaccharide-based chemotherapeutics and to highlight current developments in polysaccharide-based nanomedicines for lung cancer. |
format | Online Article Text |
id | pubmed-9782996 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97829962022-12-24 Polysaccharide-Based Nanomedicines Targeting Lung Cancer Bhat, Asif Ahmad Gupta, Gaurav Alharbi, Khalid Saad Afzal, Obaid Altamimi, Abdulmalik S. A. Almalki, Waleed Hassan Kazmi, Imran Al-Abbasi, Fahad A. Alzarea, Sami I. Chellappan, Dinesh Kumar Singh, Sachin Kumar MacLoughlin, Ronan Oliver, Brian G Dua, Kamal Pharmaceutics Review A primary illness that accounts for a significant portion of fatalities worldwide is cancer. Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer around the globe. Radiation treatment, surgery, and chemotherapy are some medical procedures used in the traditional care of lung cancer. However, these methods lack selectivity and damage nearby healthy cells. Several polysaccharide-based nanomaterials have been created to transport chemotherapeutics to reduce harmful and adverse side effects and improve response during anti-tumour reactions. To address these drawbacks, a class of naturally occurring polymers called polysaccharides have special physical, chemical, and biological characteristics. They can interact with the immune system to induce a better immunological response. Furthermore, because of the flexibility of their structures, it is possible to create multifunctional nanocomposites with excellent stability and bioavailability for the delivery of medicines to tumour tissues. This study seeks to present new views on the use of polysaccharide-based chemotherapeutics and to highlight current developments in polysaccharide-based nanomedicines for lung cancer. MDPI 2022-12-13 /pmc/articles/PMC9782996/ /pubmed/36559281 http://dx.doi.org/10.3390/pharmaceutics14122788 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Bhat, Asif Ahmad Gupta, Gaurav Alharbi, Khalid Saad Afzal, Obaid Altamimi, Abdulmalik S. A. Almalki, Waleed Hassan Kazmi, Imran Al-Abbasi, Fahad A. Alzarea, Sami I. Chellappan, Dinesh Kumar Singh, Sachin Kumar MacLoughlin, Ronan Oliver, Brian G Dua, Kamal Polysaccharide-Based Nanomedicines Targeting Lung Cancer |
title | Polysaccharide-Based Nanomedicines Targeting Lung Cancer |
title_full | Polysaccharide-Based Nanomedicines Targeting Lung Cancer |
title_fullStr | Polysaccharide-Based Nanomedicines Targeting Lung Cancer |
title_full_unstemmed | Polysaccharide-Based Nanomedicines Targeting Lung Cancer |
title_short | Polysaccharide-Based Nanomedicines Targeting Lung Cancer |
title_sort | polysaccharide-based nanomedicines targeting lung cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782996/ https://www.ncbi.nlm.nih.gov/pubmed/36559281 http://dx.doi.org/10.3390/pharmaceutics14122788 |
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