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Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients
Patients with previously diagnosed HF are at greater risk for subsequent morbidity and mortality when hospitalized for an Acute Myocardial Infarction (AMI). The purpose of our study was to describe the time trend of the incidence of emergent CABG in patients with and without HF, the clinical charact...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783056/ https://www.ncbi.nlm.nih.gov/pubmed/36556489 http://dx.doi.org/10.3390/life12122124 |
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author | Bianchi, Giacomo Zancanaro, Edoardo Margaryan, Rafik Concistré, Giovanni Varone, Egidio Simeoni, Simone Solinas, Marco |
author_facet | Bianchi, Giacomo Zancanaro, Edoardo Margaryan, Rafik Concistré, Giovanni Varone, Egidio Simeoni, Simone Solinas, Marco |
author_sort | Bianchi, Giacomo |
collection | PubMed |
description | Patients with previously diagnosed HF are at greater risk for subsequent morbidity and mortality when hospitalized for an Acute Myocardial Infarction (AMI). The purpose of our study was to describe the time trend of the incidence of emergent CABG in patients with and without HF, the clinical characteristics, outcomes, and the risk factors for mortality of surgical revascularization in the short and medium term. This was a single-center retrospective observational study of patients who underwent isolated emergency CABG from January 2009 to January 2020. A propensity-score matching analysis yielded two comparable groups (n = 430) of patients without (n = 215) and with (n = 215) heart failure. In-hospital mortality did not differ in the two groups (2.8%; p > 0.9); the patients with heart failure presented more frequently with cardiogenic shock, and there was an association with mortality and mechanical circulatory support (OR 16.7–95% CI 3.31–140; p = 0.002) and postoperative acute renal failure (OR 15.9–95% CI 0.66–203; p = 0.036). In the early- and mid-term, heart failure and NSTEMI were associated with mortality (HR 3.47–95% CI 1.15–10.5; p = 0.028), along with age (HR 1.28–95% CI 1.21–1.36; p < 0.001). Surgical revascularization offers an excellent solution for patients with acute coronary syndrome, leading to a good immediate prognosis even in those with chronic heart failure. |
format | Online Article Text |
id | pubmed-9783056 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97830562022-12-24 Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients Bianchi, Giacomo Zancanaro, Edoardo Margaryan, Rafik Concistré, Giovanni Varone, Egidio Simeoni, Simone Solinas, Marco Life (Basel) Article Patients with previously diagnosed HF are at greater risk for subsequent morbidity and mortality when hospitalized for an Acute Myocardial Infarction (AMI). The purpose of our study was to describe the time trend of the incidence of emergent CABG in patients with and without HF, the clinical characteristics, outcomes, and the risk factors for mortality of surgical revascularization in the short and medium term. This was a single-center retrospective observational study of patients who underwent isolated emergency CABG from January 2009 to January 2020. A propensity-score matching analysis yielded two comparable groups (n = 430) of patients without (n = 215) and with (n = 215) heart failure. In-hospital mortality did not differ in the two groups (2.8%; p > 0.9); the patients with heart failure presented more frequently with cardiogenic shock, and there was an association with mortality and mechanical circulatory support (OR 16.7–95% CI 3.31–140; p = 0.002) and postoperative acute renal failure (OR 15.9–95% CI 0.66–203; p = 0.036). In the early- and mid-term, heart failure and NSTEMI were associated with mortality (HR 3.47–95% CI 1.15–10.5; p = 0.028), along with age (HR 1.28–95% CI 1.21–1.36; p < 0.001). Surgical revascularization offers an excellent solution for patients with acute coronary syndrome, leading to a good immediate prognosis even in those with chronic heart failure. MDPI 2022-12-16 /pmc/articles/PMC9783056/ /pubmed/36556489 http://dx.doi.org/10.3390/life12122124 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bianchi, Giacomo Zancanaro, Edoardo Margaryan, Rafik Concistré, Giovanni Varone, Egidio Simeoni, Simone Solinas, Marco Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients |
title | Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients |
title_full | Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients |
title_fullStr | Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients |
title_full_unstemmed | Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients |
title_short | Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients |
title_sort | outcomes of emergent isolated coronary bypass grafting in heart failure patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783056/ https://www.ncbi.nlm.nih.gov/pubmed/36556489 http://dx.doi.org/10.3390/life12122124 |
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