Cargando…

Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients

Patients with previously diagnosed HF are at greater risk for subsequent morbidity and mortality when hospitalized for an Acute Myocardial Infarction (AMI). The purpose of our study was to describe the time trend of the incidence of emergent CABG in patients with and without HF, the clinical charact...

Descripción completa

Detalles Bibliográficos
Autores principales: Bianchi, Giacomo, Zancanaro, Edoardo, Margaryan, Rafik, Concistré, Giovanni, Varone, Egidio, Simeoni, Simone, Solinas, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783056/
https://www.ncbi.nlm.nih.gov/pubmed/36556489
http://dx.doi.org/10.3390/life12122124
_version_ 1784857486811987968
author Bianchi, Giacomo
Zancanaro, Edoardo
Margaryan, Rafik
Concistré, Giovanni
Varone, Egidio
Simeoni, Simone
Solinas, Marco
author_facet Bianchi, Giacomo
Zancanaro, Edoardo
Margaryan, Rafik
Concistré, Giovanni
Varone, Egidio
Simeoni, Simone
Solinas, Marco
author_sort Bianchi, Giacomo
collection PubMed
description Patients with previously diagnosed HF are at greater risk for subsequent morbidity and mortality when hospitalized for an Acute Myocardial Infarction (AMI). The purpose of our study was to describe the time trend of the incidence of emergent CABG in patients with and without HF, the clinical characteristics, outcomes, and the risk factors for mortality of surgical revascularization in the short and medium term. This was a single-center retrospective observational study of patients who underwent isolated emergency CABG from January 2009 to January 2020. A propensity-score matching analysis yielded two comparable groups (n = 430) of patients without (n = 215) and with (n = 215) heart failure. In-hospital mortality did not differ in the two groups (2.8%; p > 0.9); the patients with heart failure presented more frequently with cardiogenic shock, and there was an association with mortality and mechanical circulatory support (OR 16.7–95% CI 3.31–140; p = 0.002) and postoperative acute renal failure (OR 15.9–95% CI 0.66–203; p = 0.036). In the early- and mid-term, heart failure and NSTEMI were associated with mortality (HR 3.47–95% CI 1.15–10.5; p = 0.028), along with age (HR 1.28–95% CI 1.21–1.36; p < 0.001). Surgical revascularization offers an excellent solution for patients with acute coronary syndrome, leading to a good immediate prognosis even in those with chronic heart failure.
format Online
Article
Text
id pubmed-9783056
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-97830562022-12-24 Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients Bianchi, Giacomo Zancanaro, Edoardo Margaryan, Rafik Concistré, Giovanni Varone, Egidio Simeoni, Simone Solinas, Marco Life (Basel) Article Patients with previously diagnosed HF are at greater risk for subsequent morbidity and mortality when hospitalized for an Acute Myocardial Infarction (AMI). The purpose of our study was to describe the time trend of the incidence of emergent CABG in patients with and without HF, the clinical characteristics, outcomes, and the risk factors for mortality of surgical revascularization in the short and medium term. This was a single-center retrospective observational study of patients who underwent isolated emergency CABG from January 2009 to January 2020. A propensity-score matching analysis yielded two comparable groups (n = 430) of patients without (n = 215) and with (n = 215) heart failure. In-hospital mortality did not differ in the two groups (2.8%; p > 0.9); the patients with heart failure presented more frequently with cardiogenic shock, and there was an association with mortality and mechanical circulatory support (OR 16.7–95% CI 3.31–140; p = 0.002) and postoperative acute renal failure (OR 15.9–95% CI 0.66–203; p = 0.036). In the early- and mid-term, heart failure and NSTEMI were associated with mortality (HR 3.47–95% CI 1.15–10.5; p = 0.028), along with age (HR 1.28–95% CI 1.21–1.36; p < 0.001). Surgical revascularization offers an excellent solution for patients with acute coronary syndrome, leading to a good immediate prognosis even in those with chronic heart failure. MDPI 2022-12-16 /pmc/articles/PMC9783056/ /pubmed/36556489 http://dx.doi.org/10.3390/life12122124 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bianchi, Giacomo
Zancanaro, Edoardo
Margaryan, Rafik
Concistré, Giovanni
Varone, Egidio
Simeoni, Simone
Solinas, Marco
Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients
title Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients
title_full Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients
title_fullStr Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients
title_full_unstemmed Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients
title_short Outcomes of Emergent Isolated Coronary Bypass Grafting in Heart Failure Patients
title_sort outcomes of emergent isolated coronary bypass grafting in heart failure patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783056/
https://www.ncbi.nlm.nih.gov/pubmed/36556489
http://dx.doi.org/10.3390/life12122124
work_keys_str_mv AT bianchigiacomo outcomesofemergentisolatedcoronarybypassgraftinginheartfailurepatients
AT zancanaroedoardo outcomesofemergentisolatedcoronarybypassgraftinginheartfailurepatients
AT margaryanrafik outcomesofemergentisolatedcoronarybypassgraftinginheartfailurepatients
AT concistregiovanni outcomesofemergentisolatedcoronarybypassgraftinginheartfailurepatients
AT varoneegidio outcomesofemergentisolatedcoronarybypassgraftinginheartfailurepatients
AT simeonisimone outcomesofemergentisolatedcoronarybypassgraftinginheartfailurepatients
AT solinasmarco outcomesofemergentisolatedcoronarybypassgraftinginheartfailurepatients