Mitochondria Clumping vs. Mitochondria Fusion in CMT2A Diseases

Phenotypic variations in Charcot-Marie-Tooth disease type 2A (CMT2A) result from the many mutations in the mitochondrial fusion protein, mitofusin 2 (MFN2). While the GTPase domain mutations of MFN2 lack the ability to hydrolyze GTP and complete mitochondrial fusion, the mechanism of dysfunction in...

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Detalles Bibliográficos
Autores principales: Franco, Antonietta, Walton, Caroline E., Dang, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783122/
https://www.ncbi.nlm.nih.gov/pubmed/36556475
http://dx.doi.org/10.3390/life12122110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783122/
https://www.ncbi.nlm.nih.gov/pubmed/36556475
http://dx.doi.org/10.3390/life12122110

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