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Pathways to fatherhood: clinical experiences with assisted reproductive technology in single and coupled intended fathers

OBJECTIVE: To explore the cycle characteristics and outcomes of single and coupled intended fathers (SCIFs) using assisted reproductive technology. DESIGN: Cross-sectional study. SETTING: Multicenter, fertility practices from 2016 to 2020. PATIENT(S): In this study, cycles among SCIFs with access to...

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Autores principales: Monseur, Brent, Lee, Joseph A., Qiu, Melody, Liang, Angely, Copperman, Alan B., Leondires, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783155/
https://www.ncbi.nlm.nih.gov/pubmed/36568926
http://dx.doi.org/10.1016/j.xfre.2022.07.009
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author Monseur, Brent
Lee, Joseph A.
Qiu, Melody
Liang, Angely
Copperman, Alan B.
Leondires, Mark
author_facet Monseur, Brent
Lee, Joseph A.
Qiu, Melody
Liang, Angely
Copperman, Alan B.
Leondires, Mark
author_sort Monseur, Brent
collection PubMed
description OBJECTIVE: To explore the cycle characteristics and outcomes of single and coupled intended fathers (SCIFs) using assisted reproductive technology. DESIGN: Cross-sectional study. SETTING: Multicenter, fertility practices from 2016 to 2020. PATIENT(S): In this study, cycles among SCIFs with access to fertility coverage from 2016 to 2020 were included. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Our primary outcome was live birth rate. The secondary outcomes included the number of embryos transferred, miscarriage rate, and incidence of multifetal birth. RESULT(S): Five single and 39 coupled intended fathers completed an in vitro fertilization cycle with a majority using egg donation and an agency-based gestational carrier (69.7%, 83/119). In most couples, both partners wanted to serve as the sperm source (64.4%, 29/45). The vast majority (97.7%, 43/44) also used preimplantation genetic testing for aneuploidy. Among the embryo transfer (ET) cycles (n = 27), most consisted of a single euploid ET (74.07%, 20/27), whereas the remaining consisted of a double euploid ET (25.92%, 7/27). The SCIFs had high rates of success, with a live birth rate of 85.19% (23/27). A mean of 1.26 ± 0.44 embryos were transferred, with a majority resulting in singleton birth (70.37%, 19/27). CONCLUSION(S): Our study of SCIFs using assisted reproductive technology in the United States demonstrates that this population shares similar preferences for sperm source and the use of preimplantation genetic testing. Clinical outcomes suggest that this population is successful at achieving a live birth when using egg donation and a gestational carrier.
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spelling pubmed-97831552022-12-24 Pathways to fatherhood: clinical experiences with assisted reproductive technology in single and coupled intended fathers Monseur, Brent Lee, Joseph A. Qiu, Melody Liang, Angely Copperman, Alan B. Leondires, Mark F S Rep Original Article OBJECTIVE: To explore the cycle characteristics and outcomes of single and coupled intended fathers (SCIFs) using assisted reproductive technology. DESIGN: Cross-sectional study. SETTING: Multicenter, fertility practices from 2016 to 2020. PATIENT(S): In this study, cycles among SCIFs with access to fertility coverage from 2016 to 2020 were included. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Our primary outcome was live birth rate. The secondary outcomes included the number of embryos transferred, miscarriage rate, and incidence of multifetal birth. RESULT(S): Five single and 39 coupled intended fathers completed an in vitro fertilization cycle with a majority using egg donation and an agency-based gestational carrier (69.7%, 83/119). In most couples, both partners wanted to serve as the sperm source (64.4%, 29/45). The vast majority (97.7%, 43/44) also used preimplantation genetic testing for aneuploidy. Among the embryo transfer (ET) cycles (n = 27), most consisted of a single euploid ET (74.07%, 20/27), whereas the remaining consisted of a double euploid ET (25.92%, 7/27). The SCIFs had high rates of success, with a live birth rate of 85.19% (23/27). A mean of 1.26 ± 0.44 embryos were transferred, with a majority resulting in singleton birth (70.37%, 19/27). CONCLUSION(S): Our study of SCIFs using assisted reproductive technology in the United States demonstrates that this population shares similar preferences for sperm source and the use of preimplantation genetic testing. Clinical outcomes suggest that this population is successful at achieving a live birth when using egg donation and a gestational carrier. Elsevier 2022-08-05 /pmc/articles/PMC9783155/ /pubmed/36568926 http://dx.doi.org/10.1016/j.xfre.2022.07.009 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Monseur, Brent
Lee, Joseph A.
Qiu, Melody
Liang, Angely
Copperman, Alan B.
Leondires, Mark
Pathways to fatherhood: clinical experiences with assisted reproductive technology in single and coupled intended fathers
title Pathways to fatherhood: clinical experiences with assisted reproductive technology in single and coupled intended fathers
title_full Pathways to fatherhood: clinical experiences with assisted reproductive technology in single and coupled intended fathers
title_fullStr Pathways to fatherhood: clinical experiences with assisted reproductive technology in single and coupled intended fathers
title_full_unstemmed Pathways to fatherhood: clinical experiences with assisted reproductive technology in single and coupled intended fathers
title_short Pathways to fatherhood: clinical experiences with assisted reproductive technology in single and coupled intended fathers
title_sort pathways to fatherhood: clinical experiences with assisted reproductive technology in single and coupled intended fathers
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783155/
https://www.ncbi.nlm.nih.gov/pubmed/36568926
http://dx.doi.org/10.1016/j.xfre.2022.07.009
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