Cargando…

Nano and Microemulsions for the Treatment of Depressive and Anxiety Disorders: An Efficient Approach to Improve Solubility, Brain Bioavailability and Therapeutic Efficacy

Most drugs used for the treatment of depression, anxiety and related disorders have low absorption, high metabolism, low brain targeting and/or low water solubility, which can make it hard to formulate them at high strength and can also lead to decreased bioavailability. Incorporating these drugs in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pires, Patrícia C., Paiva-Santos, Ana Cláudia, Veiga, Francisco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783281/ https://www.ncbi.nlm.nih.gov/pubmed/36559318 http://dx.doi.org/10.3390/pharmaceutics14122825

Ejemplares similares

Nanosystems for Brain Targeting of Antipsychotic Drugs: An Update on the Most Promising Nanocarriers for Increased Bioavailability and Therapeutic Efficacy
por: Ferreira, Maria Daniela, et al.
Publicado: (2023)

Improved oral bioavailability of poorly water-soluble glimepiride by utilizing microemulsion technique
por: Li, Haiying, et al.
Publicado: (2016)

Liposome-Derived Nanosystems for the Treatment of Behavioral and Neurodegenerative Diseases: The Promise of Niosomes, Transfersomes, and Ethosomes for Increased Brain Drug Bioavailability
por: Pires, Patrícia C., et al.
Publicado: (2023)

Lipid and Polymeric Nanoparticles: Successful Strategies for Nose-to-Brain Drug Delivery in the Treatment of Depression and Anxiety Disorders
por: Alberto, Margarida, et al.
Publicado: (2022)

Toxicity Evaluation of Microemulsion (Nano Size) of Sour Cherry Kernel Extract for the Oral Bioavailability Enhancement
por: Salimi, Anayatollah, et al.
Publicado: (2014)

Microemulsion Drug Delivery System: For Bioavailability Enhancement of Ampelopsin
por: Solanki, Shailendra Singh, et al.
Publicado: (2012)

Development of Microemulsion for Solubility Enhancement of Clopidogrel
por: Patel, Vandana, et al.
Publicado: (2010)

Topical Nano and Microemulsions for Skin Delivery
por: Nastiti, Christofori M. R. R., et al.
Publicado: (2017)

Nanosystems, Drug Molecule Functionalization and Intranasal Delivery: An Update on the Most Promising Strategies for Increasing the Therapeutic Efficacy of Antidepressant and Anxiolytic Drugs
por: Antunes, Jéssica L., et al.
Publicado: (2023)

Improving water dispersibility and bioavailability of luteolin using microemulsion system
por: Miyashita, Ayaka, et al.
Publicado: (2022)

Nano- and Microemulsions in Biomedicine: From Theory to Practice
por: Nikolaev, Boris, et al.
Publicado: (2023)

Preparation, characterization and relative bioavailability of oral elemene o/w microemulsion
por: Zeng, Zhaowu, et al.
Publicado: (2010)

Utilization of Microemulsions from Rhinacanthus nasutus (L.) Kurz to Improve Carotenoid Bioavailability
por: Ho, Nai-Hsing, et al.
Publicado: (2016)

Transdermal agomelatine microemulsion gel: pyramidal screening, statistical optimization and in vivo bioavailability
por: Said, Mayada, et al.
Publicado: (2017)

Cytotoxicity and genotoxicity of nano - and microparticulate copper oxide: role of solubility and intracellular bioavailability
por: Semisch, Annetta, et al.
Publicado: (2014)

Antipsychotics-Loaded Nanometric Emulsions for Brain Delivery
por: Pires, Patrícia C., et al.
Publicado: (2022)

Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics
por: Bhalani, Dixit V., et al.
Publicado: (2022)

Enhancement of the Topical Bioavailability and Skin Whitening Effect of Genistein by Using Microemulsions as Drug Delivery Carriers
por: Vu, Quoc Lam, et al.
Publicado: (2021)

Synthesis of water-soluble ionic terpolymers by inverse microemulsion and solution polymerization methods
por: Calvillo-Muñoz, Evelyn Y., et al.
Publicado: (2022)

Drug nanoclusters formed in confined nano-cages of CD-MOF: dramatic enhancement of solubility and bioavailability of azilsartan
por: He, Yuanzhi, et al.
Publicado: (2019)

Enhanced oral bioavailability of a sterol-loaded microemulsion formulation of Flammulina velutipes, a potential antitumor drug
por: Yi, Chengxue, et al.
Publicado: (2012)

Promising Nanocarriers to Enhance Solubility and Bioavailability of Cannabidiol for a Plethora of Therapeutic Opportunities
por: Grifoni, Lucia, et al.
Publicado: (2022)

Potential of solid dispersions to enhance solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs: newer formulation techniques, current marketed scenario and patents
por: Alshehri, Sultan, et al.
Publicado: (2020)

Dehydroepiandrosterone Cocrystals with Improved Solubility and Bioavailability
por: Jiang, Yihua, et al.
Publicado: (2022)

Mechanisms of microemulsion enhancing the oral bioavailability of puerarin: comparison between oil-in-water and water-in-oil microemulsions using the single-pass intestinal perfusion method and a chylomicron flow blocking approach
por: Tang, Tian-Tian, et al.
Publicado: (2013)

Stability and solubility improvement of Sompoi (Acacia concinna Linn.) pod extract by topical microemulsion
por: Poomanee, Worrapan, et al.
Publicado: (2017)

Cyclic Glucans Enhance Solubility of Bioavailable Flavonoids
por: Park, Seyeon
Publicado: (2016)

Solubility and Bioavailability Enhancement of Oridonin: A Review
por: Zhang, Yuanyuan, et al.
Publicado: (2020)

Novel Strategies for Solubility and Bioavailability Enhancement of Bufadienolides
por: Shao, Huili, et al.
Publicado: (2021)

Microemulsions vs chitosan derivative-coated microemulsions for dermal delivery of 8-methoxypsoralen
por: Wu, Jun-Yong, et al.
Publicado: (2019)

Evaluation of Sub-acute Oral Toxicity of Lithium Carbonate Microemulsion (Nano Size) on Liver and Kidney of Mice
por: Kalantari, Heibatullah, et al.
Publicado: (2015)

Comparison of Engine Performance between Nano- and Microemulsions of Solketal Droplets Dispersed in Diesel Assisted by Microwave Irradiation
por: Lin, Cherng-Yuan, et al.
Publicado: (2019)

Catan-ionic hybrid lipidic nano-carriers for enhanced bioavailability and anti-tumor efficacy of chemodrugs
por: Liu, Bilin, et al.
Publicado: (2017)

Polymorph Impact on the Bioavailability and Stability of Poorly Soluble Drugs
por: Censi, Roberta, et al.
Publicado: (2015)

Strategies for Solubility and Bioavailability Enhancement and Toxicity Reduction of Norcantharidin
por: Liu, Qian, et al.
Publicado: (2022)

Optimized solubility and bioavailability of genistein based on cocrystal engineering
por: Wang, Zhipeng, et al.
Publicado: (2023)

Preparation and evaluation of cilnidipine microemulsion
por: Tandel, Hemal, et al.
Publicado: (2012)

Micelles, membranes, microemulsions, and monolayers
por: Gelbart, William, et al.
Publicado: (1994)

Overcoming the Cutaneous Barrier with Microemulsions
por: Lopes, Luciana B.
Publicado: (2014)

Dynamics in polyelectrolyte/microemulsion complexes
por: Simon, Miriam, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1vde8t04ihn63l6civoftl94aq