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Mechanocardiography-Based Measurement System Indicating Changes in Heart Failure Patients during Hospital Admission and Discharge

Heart failure (HF) is a disease related to impaired performance of the heart and is a significant cause of mortality and treatment costs in the world. During its progression, HF causes worsening (decompensation) periods which generally require hospital care. In order to reduce the suffering of the p...

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Autores principales: Koivisto, Tero, Lahdenoja, Olli, Hurnanen, Tero, Koskinen, Juho, Jafarian, Kamal, Vasankari, Tuija, Jaakkola, Samuli, Kiviniemi, Tuomas O., Airaksinen, K. E. Juhani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783454/
https://www.ncbi.nlm.nih.gov/pubmed/36560149
http://dx.doi.org/10.3390/s22249781
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author Koivisto, Tero
Lahdenoja, Olli
Hurnanen, Tero
Koskinen, Juho
Jafarian, Kamal
Vasankari, Tuija
Jaakkola, Samuli
Kiviniemi, Tuomas O.
Airaksinen, K. E. Juhani
author_facet Koivisto, Tero
Lahdenoja, Olli
Hurnanen, Tero
Koskinen, Juho
Jafarian, Kamal
Vasankari, Tuija
Jaakkola, Samuli
Kiviniemi, Tuomas O.
Airaksinen, K. E. Juhani
author_sort Koivisto, Tero
collection PubMed
description Heart failure (HF) is a disease related to impaired performance of the heart and is a significant cause of mortality and treatment costs in the world. During its progression, HF causes worsening (decompensation) periods which generally require hospital care. In order to reduce the suffering of the patients and the treatment cost, avoiding unnecessary hospital visits is essential, as hospitalization can be prevented by medication. We have developed a data-collection device that includes a high-quality 3-axis accelerometer and 3-axis gyroscope and a single-lead ECG. This allows gathering ECG synchronized data utilizing seismo- and gyrocardiography (SCG, GCG, jointly mechanocardiography, MCG) and comparing the signals of HF patients in acute decompensation state (hospital admission) and compensated condition (hospital discharge). In the MECHANO-HF study, we gathered data from 20 patients, who each had admission and discharge measurements. In order to avoid overfitting, we used only features developed beforehand and selected features that were not outliers. As a result, we found three important signs indicating the worsening of the disease: an increase in signal RMS (root-mean-square) strength (across SCG and GCG), an increase in the strength of the third heart sound (S3), and a decrease in signal stability around the first heart sound (S1). The best individual feature (S3) alone was able to separate the recordings, giving 85.0% accuracy and 90.9% accuracy regarding all signals and signals with sinus rhythm only, respectively. These observations pave the way to implement solutions for patient self-screening of the HF using serial measurements.
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spelling pubmed-97834542022-12-24 Mechanocardiography-Based Measurement System Indicating Changes in Heart Failure Patients during Hospital Admission and Discharge Koivisto, Tero Lahdenoja, Olli Hurnanen, Tero Koskinen, Juho Jafarian, Kamal Vasankari, Tuija Jaakkola, Samuli Kiviniemi, Tuomas O. Airaksinen, K. E. Juhani Sensors (Basel) Article Heart failure (HF) is a disease related to impaired performance of the heart and is a significant cause of mortality and treatment costs in the world. During its progression, HF causes worsening (decompensation) periods which generally require hospital care. In order to reduce the suffering of the patients and the treatment cost, avoiding unnecessary hospital visits is essential, as hospitalization can be prevented by medication. We have developed a data-collection device that includes a high-quality 3-axis accelerometer and 3-axis gyroscope and a single-lead ECG. This allows gathering ECG synchronized data utilizing seismo- and gyrocardiography (SCG, GCG, jointly mechanocardiography, MCG) and comparing the signals of HF patients in acute decompensation state (hospital admission) and compensated condition (hospital discharge). In the MECHANO-HF study, we gathered data from 20 patients, who each had admission and discharge measurements. In order to avoid overfitting, we used only features developed beforehand and selected features that were not outliers. As a result, we found three important signs indicating the worsening of the disease: an increase in signal RMS (root-mean-square) strength (across SCG and GCG), an increase in the strength of the third heart sound (S3), and a decrease in signal stability around the first heart sound (S1). The best individual feature (S3) alone was able to separate the recordings, giving 85.0% accuracy and 90.9% accuracy regarding all signals and signals with sinus rhythm only, respectively. These observations pave the way to implement solutions for patient self-screening of the HF using serial measurements. MDPI 2022-12-13 /pmc/articles/PMC9783454/ /pubmed/36560149 http://dx.doi.org/10.3390/s22249781 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Koivisto, Tero
Lahdenoja, Olli
Hurnanen, Tero
Koskinen, Juho
Jafarian, Kamal
Vasankari, Tuija
Jaakkola, Samuli
Kiviniemi, Tuomas O.
Airaksinen, K. E. Juhani
Mechanocardiography-Based Measurement System Indicating Changes in Heart Failure Patients during Hospital Admission and Discharge
title Mechanocardiography-Based Measurement System Indicating Changes in Heart Failure Patients during Hospital Admission and Discharge
title_full Mechanocardiography-Based Measurement System Indicating Changes in Heart Failure Patients during Hospital Admission and Discharge
title_fullStr Mechanocardiography-Based Measurement System Indicating Changes in Heart Failure Patients during Hospital Admission and Discharge
title_full_unstemmed Mechanocardiography-Based Measurement System Indicating Changes in Heart Failure Patients during Hospital Admission and Discharge
title_short Mechanocardiography-Based Measurement System Indicating Changes in Heart Failure Patients during Hospital Admission and Discharge
title_sort mechanocardiography-based measurement system indicating changes in heart failure patients during hospital admission and discharge
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783454/
https://www.ncbi.nlm.nih.gov/pubmed/36560149
http://dx.doi.org/10.3390/s22249781
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