In Situ Co-Amorphization of Olanzapine in the Matrix and on the Coat of Pellets

In situ amorphization is a promising approach, considered in the present work, to enhance the solubility and dissolution rate of olanzapine, while minimizing the exposure of the amorphous material to the stress conditions applied during conventional processing. The production of pellets by extrusion...

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Detalles Bibliográficos
Autores principales: da Costa, Nuno F., Azevedo, Raquel F., Lopes, João A., Fernandes, Ana I., Pinto, João F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783598/
https://www.ncbi.nlm.nih.gov/pubmed/36559080
http://dx.doi.org/10.3390/pharmaceutics14122587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783598/
https://www.ncbi.nlm.nih.gov/pubmed/36559080
http://dx.doi.org/10.3390/pharmaceutics14122587

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