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The Immunomodulator Dimethyl Itaconate Inhibits Several Key Steps of Angiogenesis in Cultured Endothelial Cells

The dimethyl derivative of the immunomodulator itaconate has been previously shown to have anti-inflammatory, anti-oxidative, and immunomodulatory effects. In the present work, we evaluate the potential of dimethyl itaconate as an anti-angiogenic compound by using cultured endothelial cells and seve...

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Detalles Bibliográficos
Autores principales: Vidal, Isabel, Fernández-Florido, Elena, Marrero, Ana Dácil, Castilla, Laura, R. Quesada, Ana, Martínez-Poveda, Beatriz, Medina, Miguel Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783644/
https://www.ncbi.nlm.nih.gov/pubmed/36555614
http://dx.doi.org/10.3390/ijms232415972