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New Guanidine Alkaloids Batzelladines O and P from the Marine Sponge Monanchora pulchra Induce Apoptosis and Autophagy in Prostate Cancer Cells

Two new guanidine alkaloids, batzelladines O (1) and P (2), were isolated from the deep-water marine sponge Monanchora pulchra. The structures of these metabolites were determined by NMR spectroscopy, mass spectrometry, and ECD. The isolated compounds exhibited cytotoxic activity in human prostate c...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Shubina, Larisa K., Makarieva, Tatyana N., Guzii, Alla G., Hauschild, Jessica, Strewinsky, Nadja, Berdyshev, Dmitrii V., Kudryashova, Ekaterina K., Menshov, Alexander S., Popov, Roman S., Dmitrenok, Pavel S., Graefen, Markus, Bokemeyer, Carsten, von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783649/
https://www.ncbi.nlm.nih.gov/pubmed/36547885
http://dx.doi.org/10.3390/md20120738