Cargando…

Pharmaceutical targeting Th2-mediated immunity enhances immunotherapy response in breast cancer

BACKGROUND: Breast cancer is a complex disease with a highly immunosuppressive tumor microenvironment, and has limited clinical response to immune checkpoint blockade (ICB) therapy. T-helper 2 (Th2) cells, an important component of the tumor microenvironment (TME), play an essential role in regulati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yuru, Sun, Jiazheng, Luo, Yachan, Liu, Jiazhou, Wang, Xiaoyu, Feng, Rui, Huang, Jing, Du, Huimin, Li, Qin, Tan, Jinxiang, Ren, Guosheng, Wang, Xiaoyi, Li, Hongzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783715/ https://www.ncbi.nlm.nih.gov/pubmed/36564797 http://dx.doi.org/10.1186/s12967-022-03807-8

Ejemplares similares

The Novel Methylation Biomarker NPY5R Sensitizes Breast Cancer Cells to Chemotherapy
por: Liu, Jiazhou, et al.
Publicado: (2022)

FGFR blockade boosts T cell infiltration into triple-negative breast cancer by regulating cancer-associated fibroblasts
por: Wu, Yushen, et al.
Publicado: (2022)

ATP2C2 Has Potential to Define Tumor Microenvironment in Breast Cancer
por: Liu, Jiazhou, et al.
Publicado: (2021)

NLRP1 Overexpression Is Correlated with the Tumorigenesis and Proliferation of Human Breast Tumor
por: Wei, Yuxian, et al.
Publicado: (2017)

Breast-Conserving Therapy Has Better Prognosis for Tumors in the Central and Nipple Portion of Breast Cancer Compared with Mastectomy: A SEER Data-Based Study
por: Wang, Jing, et al.
Publicado: (2021)

Expression patterns of E2F transcription factors and their potential prognostic roles in breast cancer
por: Li, Yunhai, et al.
Publicado: (2018)

Efficacy and safety of neoadjuvant chemotherapy regimens for triple-negative breast cancer: a network meta-analysis
por: Li, Yunhai, et al.
Publicado: (2019)

Clinicopathological Features of Breast Cancer in Relation to Exposure of Cycling Reproductive Hormones: A Multicenter Retrospective Study of 14 731 Patients Diagnosed with Invasive Breast Cancer
por: Sun, Jiazheng, et al.
Publicado: (2022)

Meta-analysis of associations between DLG5 R30Q and P1371Q polymorphisms and susceptibility to inflammatory bowel disease
por: Li, Yunhai, et al.
Publicado: (2016)

Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression
por: Yang, Dejuan, et al.
Publicado: (2018)

Circular RNA 0001073 Attenuates Malignant Biological Behaviours in Breast Cancer Cell and Is Delivered by Nanoparticles to Inhibit Mice Tumour Growth
por: Yi, Ziying, et al.
Publicado: (2020)

The transcription levels and prognostic values of seven proteasome alpha subunits in human cancers
por: Li, Yunhai, et al.
Publicado: (2016)

Gut microbiota influence immunotherapy responses: mechanisms and therapeutic strategies
por: Lu, Yuting, et al.
Publicado: (2022)

A Ribosome-Related Prognostic Signature of Breast Cancer Subtypes Based on Changes in Breast Cancer Patients’ Immunological Activity
por: Luan, Tiankuo, et al.
Publicado: (2023)

Editorial: Cancer cell-intrinsic and -extrinsic factors affecting tumor immune evasion
por: Sun, Jiazheng, et al.
Publicado: (2023)

AMPD1 Is Associated With the Immune Response and Serves as a Prognostic Marker in HER2-Positive Breast Cancer
por: Wang, Long, et al.
Publicado: (2021)

Immune Regulation of TNFAIP3 in Psoriasis through Its Association with Th1 and Th17 Cell Differentiation and p38 Activation
por: Jiang, Yanyun, et al.
Publicado: (2020)

Non-pharmaceutical interventions to optimize cancer immunotherapy
por: Boesch, Maximilian, et al.
Publicado: (2023)

Electrostatic Charge Effects on Pharmaceutical Aerosol Deposition in Human Nasal–Laryngeal Airways
por: Xi, Jinxiang, et al.
Publicado: (2014)

Case Report: Respiratory paralysis associated with polymyxin B therapy
por: Ning, Yachan, et al.
Publicado: (2022)

Engineering neoantigen vaccines to improve cancer personalized immunotherapy
por: Liu, Zaoqu, et al.
Publicado: (2022)

Regulatory T Cells Modulate DNA Vaccine Immunogenicity at Early Time via Functional CD4(+) T Cells and Antigen Duration
por: Qin, Lizeng, et al.
Publicado: (2015)

Efficacy and tolerability of immunotherapy in advanced nasopharyngeal carcinoma with or without chemotherapy: a meta-analysis
por: Xiao, Lifeng, et al.
Publicado: (2021)

Elevated profiles of peripheral Th22, Th17, Th2 cells, and decreased percentage of Th1 cells in breast cancer patients
por: Peng, Zhiguo, et al.
Publicado: (2023)

Editorial: Synthesis, Functionalization, and Clinical Translation of Pharmaceutical Biomaterials
por: Kong, Huimin, et al.
Publicado: (2021)

Insight into the Crosstalk between Photodynamic Therapy and Immunotherapy in Breast Cancer
por: Jin, Hongzhong, et al.
Publicado: (2023)

Multi-Omics Analysis of the Anti-tumor Synergistic Mechanism and Potential Application of Immune Checkpoint Blockade Combined With Lenvatinib
por: Lu, Yuting, et al.
Publicado: (2021)

Artificial intelligence applied in neoantigen identification facilitates personalized cancer immunotherapy
por: Cai, Yu, et al.
Publicado: (2023)

Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells
por: Li, Hongzhong, et al.
Publicado: (2015)

Clinicopathological Characteristics and Breast Cancer–Specific Survival of Patients With Single Hormone Receptor–Positive Breast Cancer
por: Li, Yunhai, et al.
Publicado: (2020)

Mechanisms of Cancer Resistance to Immunotherapy
por: Bai, Rilan, et al.
Publicado: (2020)

Editorial: The challenge of immunity evaluation and immunotherapy in gynecologic and urologic oncology
por: Tan, Ruirong, et al.
Publicado: (2023)

gC1qR: A New Target for Cancer Immunotherapy
por: Lei, Yanna, et al.
Publicado: (2023)

Different Expression Characteristics of LAG3 and PD-1 in Sepsis and Their Synergistic Effect on T Cell Exhaustion: A New Strategy for Immune Checkpoint Blockade
por: Niu, Bailin, et al.
Publicado: (2019)

Upregulated FADD is associated with poor prognosis, immune exhaustion, tumor malignancy, and immunotherapy resistance in patients with lung adenocarcinoma
por: He, Miao, et al.
Publicado: (2023)

The effects of irreversible electroporation triggering anti-tumor immunity and the value of its combination with immunotherapy
por: Li, Hengyu, et al.
Publicado: (2023)

Announcing the 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology: March 8–11, 2010, Malta
por: Siepmann, Juergen
Publicado: (2009)

7th International Conference on Biomedical Engineering and Pharmaceutical Sciences
Publicado: (2023)

IL-24 is the key effector of Th9 cell-mediated tumor immunotherapy
por: Chen, Jintong, et al.
Publicado: (2023)

Immune checkpoint molecules in natural killer cells as potential targets for cancer immunotherapy
por: Cao, Yuqing, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2c9vbuu2563d7pk3uvijqsd8s7