Neuronal CRMP2 phosphorylation inhibition by the flavonoid, naringenin, contributes to the reversal of spinal sensitization and arthritic pain improvement

BACKGROUND: Rheumatoid arthritis patients usually suffer from arthritic chronic pain. However, due to an incomplete understanding of the mechanisms underlying autoimmune disorders, the management of arthritic pain is unsatisfactory. Here, we investigated the analgesic effect and underlying mechanism...

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Detalles Bibliográficos
Autores principales: Jiang, Yue-Peng, Wang, Song, Lai, Wei-Dong, Wu, Xue-Qing, Jin, Yan, Xu, Zheng-Hao, Moutal, Aubin, Khanna, Rajesh, Park, Ki Duk, Shan, Zhi-Ming, Wen, Cheng-Ping, Yu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783725/
https://www.ncbi.nlm.nih.gov/pubmed/36564853
http://dx.doi.org/10.1186/s13075-022-02975-8

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