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Vitamin C alleviates LPS-induced myocardial injury by inhibiting pyroptosis via the ROS-AKT/mTOR signalling pathway

BACKGROUND: The efficacy of vitamin C in sepsis remains controversial. Whether vitamin C can alleviate lipopolysaccharide (LPS)-induced myocardial injury by inhibiting pyroptosis has not been studied. This study aimed to evaluate the effects of vitamin C on LPS-induced myocardial injury in vitro. ME...

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Detalles Bibliográficos
Autores principales: Zhang, Pu, Zang, Meirong, Sang, Zhenzhen, Wei, Yunxia, Yan, Yan, Bian, Xiaohua, Dong, Shimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783737/
https://www.ncbi.nlm.nih.gov/pubmed/36550401
http://dx.doi.org/10.1186/s12872-022-03014-9