Low-dose brain irradiation normalizes TSPO and CLUSTERIN levels and promotes the non-amyloidogenic pathway in pre-symptomatic TgF344-AD rats

Preclinical studies have recently evaluated the impact of low-dose brain radiation therapy (LD-RT) in animal models of Alzheimer’s disease (AD) showing anti-amyloid and anti-inflammatory effects of this treatment. Its effectiveness varied, however, depending on the LD-RT protocol used and the stage...

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Detalles Bibliográficos
Autores principales: Ceyzériat, Kelly, Zilli, Thomas, Millet, Philippe, Koutsouvelis, Nikolaos, Dipasquale, Giovanna, Fossey, Christine, Cailly, Thomas, Fabis, Frédéric, Frisoni, Giovanni B., Garibotto, Valentina, Tournier, Benjamin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783748/
https://www.ncbi.nlm.nih.gov/pubmed/36550510
http://dx.doi.org/10.1186/s12974-022-02673-x

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