Effect of Binding Linkers on the Efficiency and Metabolite Profile of Biomimetic Reactions Catalyzed by Immobilized Metalloporphyrin

The investigation of liver-related metabolic stability of a drug candidate is a widely used key strategy in early-stage drug discovery. Metalloporphyrin-based biomimetic catalysts are good and well-described models of the function of CyP450 in hepatocytes. In this research, the immobilization of an...

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Detalles Bibliográficos
Autores principales: Balogh, György T., Decsi, Balázs, Krammer, Réka, Kenéz, Balázs, Ender, Ferenc, Hergert, Tamás, Balogh-Weiser, Diána
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783926/
https://www.ncbi.nlm.nih.gov/pubmed/36557309
http://dx.doi.org/10.3390/metabo12121269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783926/
https://www.ncbi.nlm.nih.gov/pubmed/36557309
http://dx.doi.org/10.3390/metabo12121269

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