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Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy

BACKGROUND: Immune checkpoint blockades (ICBs) have emerged as a promising treatment for cancer. Recently, tumour mutational burden (TMB) and neoantigen load (NAL) have been proposed to be potential biomarkers to predict the efficacy of ICB; however, they were limited by difficulties in defining the...

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Detalles Bibliográficos
Autores principales:	Qiu, Jiayue, Li, Xiangmei, He, Yalan, Wang, Qian, Li, Ji, Wu, Jiashuo, Jiang, Ying, Han, Junwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9783967/ https://www.ncbi.nlm.nih.gov/pubmed/36564823 http://dx.doi.org/10.1186/s12967-022-03836-3

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