Cargando…

Severity and progression rate of periodontitis are associated with an increased risk of hypertension of patients attending a university clinic

BACKGROUND: Although periodontitis is associated with increased risk of hypertension, studies based on new periodontal disease classification is limited. We investigated whether periodontitis severity and progression rate are linked with self-reports on doctor-diagnosed hypertension in a large cohor...

Descripción completa

Detalles Bibliográficos
Autores principales: Yildirim, Burak G., Aksit, Cemilenur, Mutlu, Mesut, Ainola, Mari, Eklund, Kari K., Leskelä, Jaakko, Pussinen, Pirkko, Beklen, Arzu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784004/
https://www.ncbi.nlm.nih.gov/pubmed/36550459
http://dx.doi.org/10.1186/s12903-022-02637-w
_version_ 1784857707434475520
author Yildirim, Burak G.
Aksit, Cemilenur
Mutlu, Mesut
Ainola, Mari
Eklund, Kari K.
Leskelä, Jaakko
Pussinen, Pirkko
Beklen, Arzu
author_facet Yildirim, Burak G.
Aksit, Cemilenur
Mutlu, Mesut
Ainola, Mari
Eklund, Kari K.
Leskelä, Jaakko
Pussinen, Pirkko
Beklen, Arzu
author_sort Yildirim, Burak G.
collection PubMed
description BACKGROUND: Although periodontitis is associated with increased risk of hypertension, studies based on new periodontal disease classification is limited. We investigated whether periodontitis severity and progression rate are linked with self-reports on doctor-diagnosed hypertension in a large cohort of patients attending the periodontology clinic at the faculty of dentistry. METHODS: Archived patient files, including radiographic image records and results from full-mouth clinical periodontal examination were screened for inclusion. Data on socioeconomic factors, smoking and oral hygiene habits, and medical history were collected with a questionnaire. RESULTS: Diagnosis and background data were available for 7008 patients. The median (IQR) age was 31.0 (21.0) years; 60.1% (n = 4211) were female. Hypertension was diagnosed in 6.2% (n = 435) of patients. Both periodontitis stage and grade differed (p < 0.001) between patients with or without hypertension. Increased periodontal disease severity was associated with a 20% increasing risk for hypertension; the odds ratio (OR) was 2.63 (95% confidence interval [CI] 1.48–4.68, p < 0.001) in stage IV periodontitis. Increasing periodontitis progression rate was associated with a 35% increased risk for hypertension; the OR was 2.22 (95% CI 1.45–3.40, p < 0.001) in grade C periodontitis. CONCLUSION: Severity and progression rate of periodontitis may be independent risk factors for hypertension in this large cohort of patients attending the university periodontal department.
format Online
Article
Text
id pubmed-9784004
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-97840042022-12-24 Severity and progression rate of periodontitis are associated with an increased risk of hypertension of patients attending a university clinic Yildirim, Burak G. Aksit, Cemilenur Mutlu, Mesut Ainola, Mari Eklund, Kari K. Leskelä, Jaakko Pussinen, Pirkko Beklen, Arzu BMC Oral Health Research BACKGROUND: Although periodontitis is associated with increased risk of hypertension, studies based on new periodontal disease classification is limited. We investigated whether periodontitis severity and progression rate are linked with self-reports on doctor-diagnosed hypertension in a large cohort of patients attending the periodontology clinic at the faculty of dentistry. METHODS: Archived patient files, including radiographic image records and results from full-mouth clinical periodontal examination were screened for inclusion. Data on socioeconomic factors, smoking and oral hygiene habits, and medical history were collected with a questionnaire. RESULTS: Diagnosis and background data were available for 7008 patients. The median (IQR) age was 31.0 (21.0) years; 60.1% (n = 4211) were female. Hypertension was diagnosed in 6.2% (n = 435) of patients. Both periodontitis stage and grade differed (p < 0.001) between patients with or without hypertension. Increased periodontal disease severity was associated with a 20% increasing risk for hypertension; the odds ratio (OR) was 2.63 (95% confidence interval [CI] 1.48–4.68, p < 0.001) in stage IV periodontitis. Increasing periodontitis progression rate was associated with a 35% increased risk for hypertension; the OR was 2.22 (95% CI 1.45–3.40, p < 0.001) in grade C periodontitis. CONCLUSION: Severity and progression rate of periodontitis may be independent risk factors for hypertension in this large cohort of patients attending the university periodontal department. BioMed Central 2022-12-22 /pmc/articles/PMC9784004/ /pubmed/36550459 http://dx.doi.org/10.1186/s12903-022-02637-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Yildirim, Burak G.
Aksit, Cemilenur
Mutlu, Mesut
Ainola, Mari
Eklund, Kari K.
Leskelä, Jaakko
Pussinen, Pirkko
Beklen, Arzu
Severity and progression rate of periodontitis are associated with an increased risk of hypertension of patients attending a university clinic
title Severity and progression rate of periodontitis are associated with an increased risk of hypertension of patients attending a university clinic
title_full Severity and progression rate of periodontitis are associated with an increased risk of hypertension of patients attending a university clinic
title_fullStr Severity and progression rate of periodontitis are associated with an increased risk of hypertension of patients attending a university clinic
title_full_unstemmed Severity and progression rate of periodontitis are associated with an increased risk of hypertension of patients attending a university clinic
title_short Severity and progression rate of periodontitis are associated with an increased risk of hypertension of patients attending a university clinic
title_sort severity and progression rate of periodontitis are associated with an increased risk of hypertension of patients attending a university clinic
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784004/
https://www.ncbi.nlm.nih.gov/pubmed/36550459
http://dx.doi.org/10.1186/s12903-022-02637-w
work_keys_str_mv AT yildirimburakg severityandprogressionrateofperiodontitisareassociatedwithanincreasedriskofhypertensionofpatientsattendingauniversityclinic
AT aksitcemilenur severityandprogressionrateofperiodontitisareassociatedwithanincreasedriskofhypertensionofpatientsattendingauniversityclinic
AT mutlumesut severityandprogressionrateofperiodontitisareassociatedwithanincreasedriskofhypertensionofpatientsattendingauniversityclinic
AT ainolamari severityandprogressionrateofperiodontitisareassociatedwithanincreasedriskofhypertensionofpatientsattendingauniversityclinic
AT eklundkarik severityandprogressionrateofperiodontitisareassociatedwithanincreasedriskofhypertensionofpatientsattendingauniversityclinic
AT leskelajaakko severityandprogressionrateofperiodontitisareassociatedwithanincreasedriskofhypertensionofpatientsattendingauniversityclinic
AT pussinenpirkko severityandprogressionrateofperiodontitisareassociatedwithanincreasedriskofhypertensionofpatientsattendingauniversityclinic
AT beklenarzu severityandprogressionrateofperiodontitisareassociatedwithanincreasedriskofhypertensionofpatientsattendingauniversityclinic