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Seroprevalence of Influenza A Virus in Dromedaries in North-Western Nigeria

Although influenza A virus is endemic in wild waterfowl, domestic poultry, swine, humans, bats, cetaceans, dogs, and horses, there is a paucity of data on the potential role of camels in zoonotic transmission of the virus. To estimate the seroprevalence of the influenza A virus in camel populations,...

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Autores principales: Adamu, Andrew M., Furlong, Morgan, Ogunlade, Samson, Adikwu, Alex A., Anyang, Annabel S., Malgwi, Arhyel, Abdulrahman, Adeiza M., Bida, Nma A., Owolodun, Olajide A., Adegboye, Oyelola A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784095/
https://www.ncbi.nlm.nih.gov/pubmed/36558810
http://dx.doi.org/10.3390/pathogens11121476
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author Adamu, Andrew M.
Furlong, Morgan
Ogunlade, Samson
Adikwu, Alex A.
Anyang, Annabel S.
Malgwi, Arhyel
Abdulrahman, Adeiza M.
Bida, Nma A.
Owolodun, Olajide A.
Adegboye, Oyelola A.
author_facet Adamu, Andrew M.
Furlong, Morgan
Ogunlade, Samson
Adikwu, Alex A.
Anyang, Annabel S.
Malgwi, Arhyel
Abdulrahman, Adeiza M.
Bida, Nma A.
Owolodun, Olajide A.
Adegboye, Oyelola A.
author_sort Adamu, Andrew M.
collection PubMed
description Although influenza A virus is endemic in wild waterfowl, domestic poultry, swine, humans, bats, cetaceans, dogs, and horses, there is a paucity of data on the potential role of camels in zoonotic transmission of the virus. To estimate the seroprevalence of the influenza A virus in camel populations, four local government areas of Nigeria that share an international border with the Niger Republic were selected. Blood samples from 184 one-hump camels (dromedaries) were collected and tested for influenza IgG antigen by ELISA. Each camel’s demographic variable, such as age, gender, location, production system, and usage, was recorded. The overall seroprevalence rate of influenza virus IgG in this study was 10.33% (95%CI: 6.33–15.66%). In the bivariate model, there was no significant difference in gender, age, site location and production system, except for usage. There was a significantly lower seroprevalence rate among camels used for labour (odds ratio (OR) = 0.34, 95% CI: 0.10–0.97) than those used for meat consumption; however, not after adjusting for other variables in the model. Increase surveillance through early detection, prediction, and risk assessment of pathogens in animal reservoirs and environmental contamination as One Health strategies to reduce potential human spillover is recommended. Molecular epidemiology studies could better elucidate the role of camels in the dynamics of disease transmission pathways.
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spelling pubmed-97840952022-12-24 Seroprevalence of Influenza A Virus in Dromedaries in North-Western Nigeria Adamu, Andrew M. Furlong, Morgan Ogunlade, Samson Adikwu, Alex A. Anyang, Annabel S. Malgwi, Arhyel Abdulrahman, Adeiza M. Bida, Nma A. Owolodun, Olajide A. Adegboye, Oyelola A. Pathogens Communication Although influenza A virus is endemic in wild waterfowl, domestic poultry, swine, humans, bats, cetaceans, dogs, and horses, there is a paucity of data on the potential role of camels in zoonotic transmission of the virus. To estimate the seroprevalence of the influenza A virus in camel populations, four local government areas of Nigeria that share an international border with the Niger Republic were selected. Blood samples from 184 one-hump camels (dromedaries) were collected and tested for influenza IgG antigen by ELISA. Each camel’s demographic variable, such as age, gender, location, production system, and usage, was recorded. The overall seroprevalence rate of influenza virus IgG in this study was 10.33% (95%CI: 6.33–15.66%). In the bivariate model, there was no significant difference in gender, age, site location and production system, except for usage. There was a significantly lower seroprevalence rate among camels used for labour (odds ratio (OR) = 0.34, 95% CI: 0.10–0.97) than those used for meat consumption; however, not after adjusting for other variables in the model. Increase surveillance through early detection, prediction, and risk assessment of pathogens in animal reservoirs and environmental contamination as One Health strategies to reduce potential human spillover is recommended. Molecular epidemiology studies could better elucidate the role of camels in the dynamics of disease transmission pathways. MDPI 2022-12-05 /pmc/articles/PMC9784095/ /pubmed/36558810 http://dx.doi.org/10.3390/pathogens11121476 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Adamu, Andrew M.
Furlong, Morgan
Ogunlade, Samson
Adikwu, Alex A.
Anyang, Annabel S.
Malgwi, Arhyel
Abdulrahman, Adeiza M.
Bida, Nma A.
Owolodun, Olajide A.
Adegboye, Oyelola A.
Seroprevalence of Influenza A Virus in Dromedaries in North-Western Nigeria
title Seroprevalence of Influenza A Virus in Dromedaries in North-Western Nigeria
title_full Seroprevalence of Influenza A Virus in Dromedaries in North-Western Nigeria
title_fullStr Seroprevalence of Influenza A Virus in Dromedaries in North-Western Nigeria
title_full_unstemmed Seroprevalence of Influenza A Virus in Dromedaries in North-Western Nigeria
title_short Seroprevalence of Influenza A Virus in Dromedaries in North-Western Nigeria
title_sort seroprevalence of influenza a virus in dromedaries in north-western nigeria
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784095/
https://www.ncbi.nlm.nih.gov/pubmed/36558810
http://dx.doi.org/10.3390/pathogens11121476
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