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Bioprinted Membranes for Corneal Tissue Engineering: A Review
Corneal transplantation is considered a convenient strategy for various types of corneal disease needs. Even though it has been applied as a suitable solution for most corneal disorders, patients still face several issues due to a lack of healthy donor corneas, and rejection is another unknown risk...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784133/ https://www.ncbi.nlm.nih.gov/pubmed/36559289 http://dx.doi.org/10.3390/pharmaceutics14122797 |
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author | Orash Mahmoud Salehi, Amin Heidari-Keshel, Saeed Poursamar, Seyed Ali Zarrabi, Ali Sefat, Farshid Mamidi, Narsimha Behrouz, Mahmoud Jabbarvand Rafienia, Mohammad |
author_facet | Orash Mahmoud Salehi, Amin Heidari-Keshel, Saeed Poursamar, Seyed Ali Zarrabi, Ali Sefat, Farshid Mamidi, Narsimha Behrouz, Mahmoud Jabbarvand Rafienia, Mohammad |
author_sort | Orash Mahmoud Salehi, Amin |
collection | PubMed |
description | Corneal transplantation is considered a convenient strategy for various types of corneal disease needs. Even though it has been applied as a suitable solution for most corneal disorders, patients still face several issues due to a lack of healthy donor corneas, and rejection is another unknown risk of corneal transplant tissue. Corneal tissue engineering (CTE) has gained significant consideration as an efficient approach to developing tissue-engineered scaffolds for corneal healing and regeneration. Several approaches are tested to develop a substrate with equal transmittance and mechanical properties to improve the regeneration of cornea tissue. In this regard, bioprinted scaffolds have recently received sufficient attention in simulating corneal structure, owing to their spectacular spatial control which produces a three-cell-loaded-dimensional corneal structure. In this review, the anatomy and function of different layers of corneal tissue are highlighted, and then the potential of the 3D bioprinting technique for promoting corneal regeneration is also discussed. |
format | Online Article Text |
id | pubmed-9784133 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97841332022-12-24 Bioprinted Membranes for Corneal Tissue Engineering: A Review Orash Mahmoud Salehi, Amin Heidari-Keshel, Saeed Poursamar, Seyed Ali Zarrabi, Ali Sefat, Farshid Mamidi, Narsimha Behrouz, Mahmoud Jabbarvand Rafienia, Mohammad Pharmaceutics Review Corneal transplantation is considered a convenient strategy for various types of corneal disease needs. Even though it has been applied as a suitable solution for most corneal disorders, patients still face several issues due to a lack of healthy donor corneas, and rejection is another unknown risk of corneal transplant tissue. Corneal tissue engineering (CTE) has gained significant consideration as an efficient approach to developing tissue-engineered scaffolds for corneal healing and regeneration. Several approaches are tested to develop a substrate with equal transmittance and mechanical properties to improve the regeneration of cornea tissue. In this regard, bioprinted scaffolds have recently received sufficient attention in simulating corneal structure, owing to their spectacular spatial control which produces a three-cell-loaded-dimensional corneal structure. In this review, the anatomy and function of different layers of corneal tissue are highlighted, and then the potential of the 3D bioprinting technique for promoting corneal regeneration is also discussed. MDPI 2022-12-14 /pmc/articles/PMC9784133/ /pubmed/36559289 http://dx.doi.org/10.3390/pharmaceutics14122797 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Orash Mahmoud Salehi, Amin Heidari-Keshel, Saeed Poursamar, Seyed Ali Zarrabi, Ali Sefat, Farshid Mamidi, Narsimha Behrouz, Mahmoud Jabbarvand Rafienia, Mohammad Bioprinted Membranes for Corneal Tissue Engineering: A Review |
title | Bioprinted Membranes for Corneal Tissue Engineering: A Review |
title_full | Bioprinted Membranes for Corneal Tissue Engineering: A Review |
title_fullStr | Bioprinted Membranes for Corneal Tissue Engineering: A Review |
title_full_unstemmed | Bioprinted Membranes for Corneal Tissue Engineering: A Review |
title_short | Bioprinted Membranes for Corneal Tissue Engineering: A Review |
title_sort | bioprinted membranes for corneal tissue engineering: a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784133/ https://www.ncbi.nlm.nih.gov/pubmed/36559289 http://dx.doi.org/10.3390/pharmaceutics14122797 |
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