Formulation of Lipid-Based Nanoparticles for Simultaneous Delivery of Lapatinib and Anti-Survivin siRNA for HER2+ Breast Cancer Treatment

In this work, lipid-based nanoparticles (LBNP) were designed to combine tyrosine kinase inhibitor (TKI) Lapatinib (LAPA) with siRNA directed against apoptosis inhibitor protein Survivin (siSurvivin) in an injectable form. This nanosystem is based on lipid nanocapsules (LNCs) coated with a cationic p...

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Detalles Bibliográficos
Autores principales: Eljack, Sahar, David, Stephanie, Chourpa, Igor, Faggad, Areeg, Allard-Vannier, Emilie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784347/
https://www.ncbi.nlm.nih.gov/pubmed/36558904
http://dx.doi.org/10.3390/ph15121452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784347/
https://www.ncbi.nlm.nih.gov/pubmed/36558904
http://dx.doi.org/10.3390/ph15121452

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