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Drug Repositioning Applied to Cardiovascular Disease in Mucopolysaccharidosis
Mucopolysaccharidoses (MPS) are genetic metabolic diseases characterized by defects in the activity of lysosomal hydrolases. In MPS, secondary cell disturbance affects pathways related to cardiovascular disorders. Hence, the study aimed to identify MPS-related drugs targeting cardiovascular disease...
Autores principales: | Villalba Silva, Gerda Cristal, Steindorff, Thiago, Silvestri Schuh, Roselena, Cardoso Flores, Natalia, Matte, Ursula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784427/ https://www.ncbi.nlm.nih.gov/pubmed/36556450 http://dx.doi.org/10.3390/life12122085 |
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