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Dual-Enhanced Pluronic Nanoformulated Methotrexate-Based Treatment Approach for Breast Cancer: Development and Evaluation of In Vitro and In Vivo Efficiency

Breast cancer is a prevalent tumor and causes deadly metastatic complications. Myriad cancer types, including breast cancer, are effectively treated by methotrexate (MTX). However, MTX hydrophobicity, adverse effects and the development of resistance have inspired a search for new effective strategi...

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Detalles Bibliográficos
Autores principales: Mansour, Amira, Mahmoud, Mohamed Y., Bakr, Alaa F., Ghoniem, Monira G., Adam, Fatima A., El-Sherbiny, Ibrahim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784442/
https://www.ncbi.nlm.nih.gov/pubmed/36559161
http://dx.doi.org/10.3390/pharmaceutics14122668