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Viral Coinfections

In nature, viral coinfection is as widespread as viral infection alone. Viral coinfections often cause altered viral pathogenicity, disrupted host defense, and mixed-up clinical symptoms, all of which result in more difficult diagnosis and treatment of a disease. There are three major virus–virus in...

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Detalles Bibliográficos
Autores principales: Du, Yanting, Wang, Chen, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784482/
https://www.ncbi.nlm.nih.gov/pubmed/36560647
http://dx.doi.org/10.3390/v14122645
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author Du, Yanting
Wang, Chen
Zhang, Ying
author_facet Du, Yanting
Wang, Chen
Zhang, Ying
author_sort Du, Yanting
collection PubMed
description In nature, viral coinfection is as widespread as viral infection alone. Viral coinfections often cause altered viral pathogenicity, disrupted host defense, and mixed-up clinical symptoms, all of which result in more difficult diagnosis and treatment of a disease. There are three major virus–virus interactions in coinfection cases: viral interference, viral synergy, and viral noninterference. We analyzed virus–virus interactions in both aspects of viruses and hosts and elucidated their possible mechanisms. Finally, we summarized the protocol of viral coinfection studies and key points in the process of virus separation and purification.
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spelling pubmed-97844822022-12-24 Viral Coinfections Du, Yanting Wang, Chen Zhang, Ying Viruses Review In nature, viral coinfection is as widespread as viral infection alone. Viral coinfections often cause altered viral pathogenicity, disrupted host defense, and mixed-up clinical symptoms, all of which result in more difficult diagnosis and treatment of a disease. There are three major virus–virus interactions in coinfection cases: viral interference, viral synergy, and viral noninterference. We analyzed virus–virus interactions in both aspects of viruses and hosts and elucidated their possible mechanisms. Finally, we summarized the protocol of viral coinfection studies and key points in the process of virus separation and purification. MDPI 2022-11-26 /pmc/articles/PMC9784482/ /pubmed/36560647 http://dx.doi.org/10.3390/v14122645 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Du, Yanting
Wang, Chen
Zhang, Ying
Viral Coinfections
title Viral Coinfections
title_full Viral Coinfections
title_fullStr Viral Coinfections
title_full_unstemmed Viral Coinfections
title_short Viral Coinfections
title_sort viral coinfections
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784482/
https://www.ncbi.nlm.nih.gov/pubmed/36560647
http://dx.doi.org/10.3390/v14122645
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