Cargando…
Structural Pharmacology of Cation-Chloride Cotransporters
Loop and thiazide diuretics have been cornerstones of clinical management of hypertension and fluid overload conditions for more than five decades. The hunt for their molecular targets led to the discovery of cation-chloride cotransporters (CCCs) that catalyze electroneutral movement of Cl(−) togeth...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784483/ https://www.ncbi.nlm.nih.gov/pubmed/36557113 http://dx.doi.org/10.3390/membranes12121206 |