Cargando…
Structural Pharmacology of Cation-Chloride Cotransporters
Loop and thiazide diuretics have been cornerstones of clinical management of hypertension and fluid overload conditions for more than five decades. The hunt for their molecular targets led to the discovery of cation-chloride cotransporters (CCCs) that catalyze electroneutral movement of Cl(−) togeth...
Autores principales: | Zhao, Yongxiang, Cao, Erhu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784483/ https://www.ncbi.nlm.nih.gov/pubmed/36557113 http://dx.doi.org/10.3390/membranes12121206 |
Ejemplares similares
-
Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide
por: Zhao, Yongxiang, et al.
Publicado: (2022) -
Structure of the human cation–chloride cotransport KCC1 in an outward-open state
por: Zhao, Yongxiang, et al.
Publicado: (2022) -
Structure of the human cation–chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy
por: Yang, Xiaoyong, et al.
Publicado: (2020) -
Pharmacological inhibition of cation-chloride cotransporters for neurological diseases
por: Nepomuceno, Rachel, et al.
Publicado: (2015) -
Author Correction: Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy
por: Yang, Xiaoyong, et al.
Publicado: (2020)