Cargando…

Scheimpflug-Derived Corneal Lower and Higher Order Aberrations Post Intrastromal Corneal Ring Segments for Keratoconus

Intrastromal corneal ring segments (ICRS) improve corneal topographic symmetry and reduce corneal aberrations through regularization of the corneal surface, thereby functioning as a viable surgical intervention for patients with keratoconus. This study aims to evaluate changes in lower- (LOAs) and h...

Descripción completa

Detalles Bibliográficos
Autores principales: M. van den Berg, Roberta, B. van den Berg, Arthur, Dodhia, Maya, Shahid, Michel, Jammal, Alessandro A., de Freitas, Denise, Rocha, Karolinne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784986/
https://www.ncbi.nlm.nih.gov/pubmed/36548938
http://dx.doi.org/10.3390/vision6040076
_version_ 1784857943137583104
author M. van den Berg, Roberta
B. van den Berg, Arthur
Dodhia, Maya
Shahid, Michel
Jammal, Alessandro A.
de Freitas, Denise
Rocha, Karolinne M.
author_facet M. van den Berg, Roberta
B. van den Berg, Arthur
Dodhia, Maya
Shahid, Michel
Jammal, Alessandro A.
de Freitas, Denise
Rocha, Karolinne M.
author_sort M. van den Berg, Roberta
collection PubMed
description Intrastromal corneal ring segments (ICRS) improve corneal topographic symmetry and reduce corneal aberrations through regularization of the corneal surface, thereby functioning as a viable surgical intervention for patients with keratoconus. This study aims to evaluate changes in lower- (LOAs) and higher-order aberrations (HOAs) amongst varying pupil sizes pre- and post- ICRS implantation in keratoconus patients. We specifically investigate the impact of pupil size on total corneal HOAs up to the 6th order. Twenty-one eyes that underwent ICRS implantation were included in this prospective interventional study. LOAs and HOAs measurements at the 6 mm, 4 mm, and 2 mm pupil diameters were collected preoperatively and at 6 months postoperatively using the Zernicke analysis function on a Scheimpflug device. ICRS implantation demonstrated a statistically significant effect in vertical coma with a −0.23 reduction (p = 0.015) for a 4 mm pupil size and a −1.384 reduction (p < 0.001) for 6 mm, with no significant effect at 2 mm. Horizontal coma, astigmatism 0°, astigmatism 45°, trefoil 5th order 30°, and RMS HOA demonstrated significant reductions at 4 mm or 6 mm pupil sizes but not at 2 mm. Our analysis demonstrates a favorable effect of ICRS implantation on larger pupil sizes, suggesting the importance of pupil size as it correlates with HOAs reduction.
format Online
Article
Text
id pubmed-9784986
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-97849862022-12-24 Scheimpflug-Derived Corneal Lower and Higher Order Aberrations Post Intrastromal Corneal Ring Segments for Keratoconus M. van den Berg, Roberta B. van den Berg, Arthur Dodhia, Maya Shahid, Michel Jammal, Alessandro A. de Freitas, Denise Rocha, Karolinne M. Vision (Basel) Article Intrastromal corneal ring segments (ICRS) improve corneal topographic symmetry and reduce corneal aberrations through regularization of the corneal surface, thereby functioning as a viable surgical intervention for patients with keratoconus. This study aims to evaluate changes in lower- (LOAs) and higher-order aberrations (HOAs) amongst varying pupil sizes pre- and post- ICRS implantation in keratoconus patients. We specifically investigate the impact of pupil size on total corneal HOAs up to the 6th order. Twenty-one eyes that underwent ICRS implantation were included in this prospective interventional study. LOAs and HOAs measurements at the 6 mm, 4 mm, and 2 mm pupil diameters were collected preoperatively and at 6 months postoperatively using the Zernicke analysis function on a Scheimpflug device. ICRS implantation demonstrated a statistically significant effect in vertical coma with a −0.23 reduction (p = 0.015) for a 4 mm pupil size and a −1.384 reduction (p < 0.001) for 6 mm, with no significant effect at 2 mm. Horizontal coma, astigmatism 0°, astigmatism 45°, trefoil 5th order 30°, and RMS HOA demonstrated significant reductions at 4 mm or 6 mm pupil sizes but not at 2 mm. Our analysis demonstrates a favorable effect of ICRS implantation on larger pupil sizes, suggesting the importance of pupil size as it correlates with HOAs reduction. MDPI 2022-12-14 /pmc/articles/PMC9784986/ /pubmed/36548938 http://dx.doi.org/10.3390/vision6040076 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
M. van den Berg, Roberta
B. van den Berg, Arthur
Dodhia, Maya
Shahid, Michel
Jammal, Alessandro A.
de Freitas, Denise
Rocha, Karolinne M.
Scheimpflug-Derived Corneal Lower and Higher Order Aberrations Post Intrastromal Corneal Ring Segments for Keratoconus
title Scheimpflug-Derived Corneal Lower and Higher Order Aberrations Post Intrastromal Corneal Ring Segments for Keratoconus
title_full Scheimpflug-Derived Corneal Lower and Higher Order Aberrations Post Intrastromal Corneal Ring Segments for Keratoconus
title_fullStr Scheimpflug-Derived Corneal Lower and Higher Order Aberrations Post Intrastromal Corneal Ring Segments for Keratoconus
title_full_unstemmed Scheimpflug-Derived Corneal Lower and Higher Order Aberrations Post Intrastromal Corneal Ring Segments for Keratoconus
title_short Scheimpflug-Derived Corneal Lower and Higher Order Aberrations Post Intrastromal Corneal Ring Segments for Keratoconus
title_sort scheimpflug-derived corneal lower and higher order aberrations post intrastromal corneal ring segments for keratoconus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9784986/
https://www.ncbi.nlm.nih.gov/pubmed/36548938
http://dx.doi.org/10.3390/vision6040076
work_keys_str_mv AT mvandenbergroberta scheimpflugderivedcorneallowerandhigherorderaberrationspostintrastromalcornealringsegmentsforkeratoconus
AT bvandenbergarthur scheimpflugderivedcorneallowerandhigherorderaberrationspostintrastromalcornealringsegmentsforkeratoconus
AT dodhiamaya scheimpflugderivedcorneallowerandhigherorderaberrationspostintrastromalcornealringsegmentsforkeratoconus
AT shahidmichel scheimpflugderivedcorneallowerandhigherorderaberrationspostintrastromalcornealringsegmentsforkeratoconus
AT jammalalessandroa scheimpflugderivedcorneallowerandhigherorderaberrationspostintrastromalcornealringsegmentsforkeratoconus
AT defreitasdenise scheimpflugderivedcorneallowerandhigherorderaberrationspostintrastromalcornealringsegmentsforkeratoconus
AT rochakarolinnem scheimpflugderivedcorneallowerandhigherorderaberrationspostintrastromalcornealringsegmentsforkeratoconus